Segmental versus Extended Resection for Colon Cancer in Lynch's Syndrome

被引：0

作者：

Hendren, Jared R. ^{[1
,2
]}

Sommovilla, Josh ^{[1
,2
]}

机构：

[1] Cleveland Clin Fdn, Digest Dis & Surg Inst, Dept Colon & Rectal Surg, 9500 Euclid Ave, Cleveland, OH 44195 USA

[2] Cleveland Clin Fdn, Sanford R Weiss MD Ctr Hereditary Colorectal Neopl, Cleveland, OH USA

来源：

CLINICS IN COLON AND RECTAL SURGERY | 2025年

关键词：

colon cancer; Lynch's syndrome; mismatch repair; colectomy; cancer surveillance; METACHRONOUS COLORECTAL-CANCER; QUALITY-OF-LIFE; RECTAL-CANCER; COLECTOMY; RISK; SURGERY; MORBIDITY; SURVIVAL; CARRIERS; ASPIRIN;

D O I：

10.1055/s-0044-1801380

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Lynch's syndrome is a common cause of hereditary colorectal cancer (CRC), resulting in higher risk of CRC and development of subsequent, metachronous CRC (mCRC). Beyond treating the primary cancer, surgeons and patients must decide on whether performing an extended colectomy, to reduce the risk of mCRC, is worth the change in function that comes with the larger operation. Considerations include likelihood for mCRC, morbidity and quality of life after resection, impact of pathogenic variant, and certain other cancer risk reduction options. The contemporary evidence to guide these decisions is reviewed herein.

引用

页数：5

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