Scandium(III)-Catalyzed N-Alkylation of Carbazoles with Alcohols

被引：0

作者：

Niu, Yu-Dan ^{[1
]}

Lv, Pei ^{[2
]}

Hu, Hao-Lan ^{[1
]}

Shi, Jianghuan ^{[2
]}

Chen, Peng ^{[1
]}

Jiang, Yi-Jun ^{[1
]}

机构：

[1] Ningbo Univ, Sch Mat Sci & Chem Engn, Key Lab Adv Mass Spectrometry & Mol Anal Zhejiang, Inst Mass Spectrometry, Ningbo 315211, Zhejiang, Peoples R China

[2] Ningbo Inst Measurement & Testing, Ningbo Inspect & Testing Ctr New Mat, Ningbo 315048, Peoples R China

来源：

SYNTHESIS-STUTTGART | 2025年 / 57卷 / 06期

关键词：

N-alkylation; carbazoles; benzylic alcohols; scandium-catalysis; heterocycles; DERIVATIVES;

D O I：

10.1055/a-2502-7704

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A general and efficient protocol has been developed for the N-alkylation of carbazoles with benzylic alcohols via scandium-catalyzed reaction. This transformation proceeds smoothly under an air atmosphere and features simple reaction conditions and wide substrate scope, which deliver a variety of N-alkylated carbazoles with up to 99%yields and broad functional group compatibilities.

引用

页码：1223 / 1229

页数：7

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