Process synthesis, design and techno-economic assessment of bio-succinic acid production

被引:1
作者
Melitos, George [1 ]
Misailidis, Nikiforos [2 ]
Petrides, Demetri [2 ]
Georgiadis, Michael C. [1 ]
机构
[1] Aristotle Univ Thessaloniki, Sch Engn, Dept Chem Engn, POB 455, Thessaloniki 54124, Greece
[2] Intelligen Inc, 117 Country View Dr, Freehold, NJ 07728 USA
关键词
Succinic acid; Fermentation; Bioprocess modelling; Techno-economic Assessment; Optimization; FERMENTATIVE PRODUCTION; GLYCEROL; RECOVERY; STRATEGY; BROTHS;
D O I
10.1016/j.fbp.2024.11.020
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
This work investigates the potential of different fermentation feedstocks towards succinic acid production. Three alternative flowsheets were constructed and modelled in SuperPro DesignerTM, utilizing different fermentation substrates: crude glycerol (a by-product of the biodiesel industry), a commercial 95 % glucose syrup and pure glycerol. Techno-economic analysis of the modelled plants showed that all three potential investments can be economically profitable, with the crude glycerol case as the most promising one. The succinic acid production cost for the crude glycerol scenario is estimated at 3.57 $/kg, while a thorough study of the capacity effect to the economics showed that it could drop as low as $2.6 $/kg. Parametric analysis and optimization performed on a flowsheet level, indicated opportunities for lowering the production cost down to 3 $/kg, a value that could pave the framework for a further potential decrease in the selling price of the product.
引用
收藏
页码:224 / 237
页数:14
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