Total Synthesis of trans-4' a-Methyl-3',4' a,9',10',10' a-hexahydro- spiro[cyclobutane-1,1'(2H)-phenanthrene]

被引：1

作者：

Dai, Weihao ^{[1
]}

Huo, Chenyu ^{[1
]}

Zheng, Tianlu ^{[1
]}

Zhu, Daoyong ^{[1
]}

Wang, Shaohua ^{[1
]}

机构：

[1] Lanzhou Univ, Sch Pharm, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 44卷 / 11期

基金：

国家重点研发计划;

关键词：

trans-4' a-methyl-3',4' a,9',10',10' a-hexahydro-spiro[cyclobutane-1,1'(2 H )-phenanthrene; total synthesis; natural product; ABIETANE DITERPENOIDS;

D O I：

10.6023/cjoc202404026

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The efficient total synthesis of trans-4' a-methyl-3',4' a ,9',10',10' a-hexahydro-spiro[cyclobutane-1,1'(2 H )- phenanthrene] has been accomplished starting from commercially available 3-phenylpropanal by two routes which take Au-catalyzed 1,3-acyloxy migration/cyclization cascade and InI3-catalyzed polyene-type cyclization as the key synthesis steps, respectively.

引用

页码：3386 / 3391

页数：6

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