ALTERATION OF GABA LEVELS IN OVARY AND FALLOPIAN-TUBE OF THE PREGNANT RAT

被引:18
作者
ERDO, SL [1 ]
机构
[1] GEDEON RICHTER LTD, CHEM WORKS, PHARMACOL RES CTR, POB 27, H-1475 BUDAPEST 10, HUNGARY
关键词
D O I
10.1016/0024-3205(84)90683-0
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The concentration and the total quantity of GABA were determined in ovary and Fallopian tube of the rat on day 3, 7, 14 and 21 of pregnancy and the values were compared with a diestrous control group. In ovary, both GABA concentration and total GABA content gradually elevated up to day 14 of gestation but, thereafter, the diminution of the 2 parameters was observed. The GABA concentrations in Fallopian tube were strongly reduced during pregnancy, and the total amount of the amino acid in this organ also decreased markedly. The significant alterations of GABA levels in both organs suggest a possible correlation between the functional status and GABA content of ovary and Fallopian tube of the pregnant rat.
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页码:1879 / 1884
页数:6
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