Anaphylaxis biomarkers: present and future

被引：0
作者：
Pampura, Alexander [1 ,2 ]
Esakova, Natalia [2 ]
Zimin, Sergey [1 ]
Filippova, Evgenia [2 ]
机构：
[1] Morozov Childrens City Hosp, Moscow, Russia
[2] Pirogov Russian Natl Res Med Univ, Russian Minist Hlth, Veltischev Res & Clin Inst Pediat & Pediat Surg, Taldomskaya St, Moscow 2125412, Russia
来源：
EUROPEAN ANNALS OF ALLERGY AND CLINICAL IMMUNOLOGY | 2024年 / 56卷 / 06期
关键词：
Biomarkers; anaphylaxis; allergy; predictors; tryptase; PLATELET-ACTIVATING-FACTOR; POSTMORTEM DIAGNOSIS; ALLERGIC REACTIONS; TRYPTASE LEVELS; HISTAMINE; MARKERS; HYPERSENSITIVITY; ACETYLHYDROLASE; CHYMASE; CCL2;
D O I：
10.23822/EurAnnACI.1764-1489.350
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Anaphylaxis is a severe, rapidly developing, and life-threatening systemic hypersensitivity reaction. The diagnosis of anaphylaxis is primarily clinical. Numerous studies on the mechanisms and the biomarkers of the disease are initiated every year. The biomarkers of anaphylaxis may become an important tool for the diagnosis, prevention, repeated risk assessment, severity stratification, and new therapeutic strategies for treatment of the disease. Various immune and non-immune mediators produced and released by effector cell populations are currently considered as biomarkers of anaphylaxis. Here, we review the current data on potential biomarkers of anaphylaxis and the possibilities and perspectives for their use in future clinical practice.
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页码：243 / 251
页数：9
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