In this investigation, Ti6Al4V was used as the base material for the shot peening process. Three major influencing parameters such as peening time, peening distance, and peening pressure were examined. The substrate was shot peened with stainless steel shot, with an average diameter of 0.6mm. The process parameters were optimized using the statistical tool Response Surface Methodology. A three-factor, five-level composite design matrix was employed to minimize the number of trial runs. The effect of shot peening parameters on hardness, surface roughness, and coefficient of friction was optimized. The adequacy of the model was checked using an analysis of variance. From the test results, it was observed that the peening performed with a shot peening time of 20s, a peening distance of 100mm, and a peening pressure of 3 bar resulted in a higher hardness of 433 VHN, a surface roughness of 5.8, and a coefficient of friction of 0.22. This may be attributed to the optimal residual compressive strength achieved through the shot peening process.