Gigantic retroperitoneal pararenal ancient schwannoma masquerading as a mesenchymal malignancy: A diagnostic conundrum

被引：0

作者：

Aggarwal, Neha ^{[1
]}

Malik, Shaivy ^{[1
]}

Ahluwalia, Charanjeet ^{[1
]}

机构：

[1] Vardhman Mahavir Med Coll & Safdarjung Hosp, Dept Pathol, Room 403, New Delhi 110029, India

来源：

UROLOGY CASE REPORTS | 2025年 / 58卷

关键词：

Ancient schwannoma; Pararenal mass; Surgical excision; Neoplasm; Mesenchymal malignancy; Schwannoma;

D O I：

10.1016/j.eucr.2024.102920

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Ancient schwannoma is a rare benign variant of schwannoma with marked degenerative changes, often mimicking malignancies, particularly when retroperitoneal and pararenal. A 34-year-old woman presented with a rapidly growing 15 cm retroperitoneal pararenal mass. Imaging suggested an aggressive malignancy. Surgical resection and histopathology revealed a well-encapsulated tumor with degenerative changes, nuclear atypia, and strong S100 positivity, confirming ancient schwannoma. Complete excision achieved negative margins, and follow-up showed no recurrence. Diagnostic challenges arise from its rarity and atypical features. Histopathology is crucial for differentiation from malignancies. Ancient schwannomas should be considered for large retroperitoneal masses to ensure accurate diagnosis and management.

引用

页数：5