Perfusion Computed Tomography for Assessing Pancreas Graft Volumetric Perfusion After Simultaneous Pancreas and Kidney Transplantation

被引:0
|
作者
Dmitriev, Ilya V. [1 ,2 ]
Muslimov, Rustam Sh. [1 ]
Anisimov, Yuriy A. [1 ,3 ]
Shchelykalina, Svetlana P. [2 ]
Grigorieva, Elena V. [3 ]
Shchekoturov, Igor O. [4 ]
Serova, Natalya S. [4 ]
Ternovoy, Sergey K. [4 ]
机构
[1] Sklifosovsky Res Inst Emergency Med, Moscow 129090, Russia
[2] Pirogov Russian Natl Res Med Univ, Dept Med Cybernet & Comp Sci MBF, Moscow 117997, Russia
[3] FSBEI HE ROSUNIMED MOH Russia, Clin Med Ctr, Radiol Dept, Moscow 127473, Russia
[4] IM Sechenov First Moscow State Med Univ, Dept Radiol & Radiotherapy, Moscow 119991, Russia
关键词
pancreas transplantation; pancreas graft revascularization; perfusion computed tomography; CT PERFUSION; ADENOCARCINOMA; NECROSIS; PREDICT;
D O I
10.3390/diagnostics14212361
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: There is paucity of data in the available medical literature regarding the parameters of the volumetric perfusion of pancreas grafts. Methods: From 5 February 2016 to 23 December 2021, we performed perfusion computed tomography in 41 patients at different times after simultaneous pancreas and kidney transplantation. The study group consisted of 18 men (44%) and 23 women (56%) with a long history of type 1 diabetes mellitus complicated by terminal chronic renal failure. The results of the perfusion computed tomography of the pancreas graft were studied, and the effects of post-transplantation timing and graft revascularization peculiarities on volumetric perfusion parameters were evaluated. Results: The median arterial blood flow, arterial blood volume, and permeability of the pancreas graft were 115.1 [99.7;130.3] mL/100 mL/min, 46.7 [37.4;56.9] mL/min, and 8.6 [4.1;11.4] mL/100 mL/min, respectively. No statistically significant differences in the averaged perfusion values were found in the head, body, and tail of the pancreas graft. The post-transplantation timing and the number of arteries involved in graft revascularization did not have a significant effect on the volumetric perfusion of the graft. Conclusion: The volumetric perfusion results of the pancreas graft correspond to those obtained in the study of pancreatic perfusion in healthy participants.
引用
收藏
页数:12
相关论文
共 50 条
  • [1] THE IMPACT OF NORMOTHERMIC REGIONAL PERFUSION ON SIMULTANEOUS KIDNEY AND PANCREAS TRANSPLANTATION
    Richards, James
    Spiers, Harry
    Fedotovs, Arturs
    Paul, Subhankar
    Watson, Christopher
    TRANSPLANT INTERNATIONAL, 2021, 34 : 205 - 205
  • [2] Islet Transplantation after Simultaneous Pancreas-Kidney Transplantation and Pancreas Graft Failure
    Gerber, Philipp A.
    Zullig, Richard
    Mueller, Markus
    Hechel-Hammer, Lukas
    Weber, Markus
    Spinas, Giatgen A.
    Lehmann, Roger
    DIABETES, 2009, 58 : A501 - A501
  • [3] Risk Factors for Delayed Pancreas Graft Function after Simultaneous Pancreas Kidney Transplantation and the Impact on Pancreas Graft Outcome
    Baitello, Marina
    Coutinho, Luciano S.
    Rangel, Erika B.
    Melaragno, Claudio S.
    Pestana, Jose Osmar M.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2010, 10 : 547 - 547
  • [4] SERIAL RADIONUCLIDE DETERMINATIONS OF GRAFT PERFUSION IN PANCREAS TRANSPLANTATION
    TEULE, GJJ
    LEUNISSEN, KML
    HALDERS, SGEA
    KEMERINK, GJ
    VANLINGEN, A
    KOOTSTRA, G
    VANHOOFF, JP
    TRANSPLANTATION PROCEEDINGS, 1989, 21 (01) : 2795 - 2796
  • [5] Islet Transplantation Following Pancreas Graft Failure after Simultaneous Pancreas-Kidney Transplantation.
    Lehmann, R.
    Gerber, P. A.
    Zullig, R.
    Spinas, G. A.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2012, 12 : 402 - 402
  • [6] Impact of Early Pancreas Graft Failure on Patient and Kidney Graft Survival After Simultaneous Pancreas and Kidney Transplantation (SPK).
    Gruessner, A.
    Laftavi, M.
    Whittaker, V.
    Acun, Z.
    Pankowycz, O.
    Gruessner, R.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2017, 17 : 687 - 687
  • [7] Formation of Collateral Veins in a Graft Pancreas After a Simultaneous Pancreas and Kidney Transplantation: A Case Report
    Choi, B. H.
    Lee, H. Y.
    Park, Y. M.
    Yang, K. H.
    Ryu, J. H.
    Chu, C. W.
    TRANSPLANTATION PROCEEDINGS, 2015, 47 (07) : 2270 - 2273
  • [8] Normothermic Regional Perfusion in Controlled Donation After Circulatory Determination of Death Simultaneous Pancreas - Kidney Transplantation
    Gomez-Duenas, Gonzalo
    Duran, Manuel
    Calleja-Lozano, Rafael
    Arjona-Sanchez, Alvaro
    Sanchez-Hidalgo, Juan Manuel
    Rodriguez-Ortiza, Lidia
    Ayllon-Teran, Maria Dolores
    Campos-Hernandezd, Juan Pablo
    Rodriguez-Benot, Alberto
    Briceno, Javier
    TRANSPLANTATION PROCEEDINGS, 2023, 55 (10) : 2259 - 2261
  • [9] Kidney Failure is Associated with Worse Pancreas Graft Survival in Simultaneous Pancreas and Kidney Transplantation
    Girman, Peter
    Lipar, Kvetoslav
    Marada, Tomas
    Kocik, Matej
    Koznarova, Radomira
    Fronek, Jiri
    Saudek, Frantisek
    TRANSPLANTATION, 2018, 102 : S238 - S238
  • [10] PANCREAS AND KIDNEY GRAFT SURVIVAL IN RECIPIENTS OLDER THAN 60 YEAR AFTER SIMULTANEOUS PANCREAS AND KIDNEY TRANSPLANTATION
    Girman, Peter
    Lipar, Kvetoslav
    Kocik, Matej
    Marada, Tomas
    Fronek, Jiri
    Saudek, Frantisek
    TRANSPLANT INTERNATIONAL, 2017, 30 : 241 - 242