Th17 Cells in Cardiovascular Disease

被引:0
|
作者
Yang, Ke [1 ,2 ]
Liu, Qianqian [1 ,2 ]
Fan, Aodi [1 ,2 ]
Lin, Hanqing [1 ,2 ]
Wang, Xizheng [1 ]
Cui, Tianyi [1 ]
Fan, Guanwei [1 ,2 ]
Li, Lan [1 ]
机构
[1] Tianjin Univ Tradit Chinese Med, State Key Lab Modern Chinese Med, Key Lab Pharmacol Tradit Chinese Med Formulae, Minist Educ, Tianjin, Peoples R China
[2] Tianjin Univ Tradit Chinese Med, Teaching Hosp 1, Natl Clin Res Ctr Chinese Med Acupuncture & Moxibu, State Key Lab Component Based Chinese Med, Tianjin, Peoples R China
关键词
cardiovascular disease; IL-17; immunity; Th17; T-CELLS; INTERLEUKIN-17; MYOCARDITIS; DISTINCT; LINEAGE; IL-17;
D O I
10.1002/cbf.70069
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Recent research has shown a strong link between Th17 cells and their cytokine IL-17, and various cardiovascular diseases such as atherosclerosis, myocardial infarction, myocarditis, and arrhythmia. Moreover, Th17 cell signalling is likely to be a key factor in cardiovascular disease. Here, we summarize recent advances in the source, function, regulation, and the effects of Th17 signaling in cardiovascular disease. Research on Th17 will suggest more specific strategies to manipulate these functions. Thus, effective treatment of cardiovascular disease and future clinical treatment will be possible.
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页数:10
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