Th17 Cells in Cardiovascular Disease

被引：0
|
作者：
Yang, Ke [1 ,2 ]
Liu, Qianqian [1 ,2 ]
Fan, Aodi [1 ,2 ]
Lin, Hanqing [1 ,2 ]
Wang, Xizheng [1 ]
Cui, Tianyi [1 ]
Fan, Guanwei [1 ,2 ]
Li, Lan [1 ]
机构：
[1] Tianjin Univ Tradit Chinese Med, State Key Lab Modern Chinese Med, Key Lab Pharmacol Tradit Chinese Med Formulae, Minist Educ, Tianjin, Peoples R China
[2] Tianjin Univ Tradit Chinese Med, Teaching Hosp 1, Natl Clin Res Ctr Chinese Med Acupuncture & Moxibu, State Key Lab Component Based Chinese Med, Tianjin, Peoples R China
来源：
CELL BIOCHEMISTRY AND FUNCTION | 2025年 / 43卷 / 04期
关键词：
cardiovascular disease; IL-17; immunity; Th17; T-CELLS; INTERLEUKIN-17; MYOCARDITIS; DISTINCT; LINEAGE; IL-17;
D O I：
10.1002/cbf.70069
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Recent research has shown a strong link between Th17 cells and their cytokine IL-17, and various cardiovascular diseases such as atherosclerosis, myocardial infarction, myocarditis, and arrhythmia. Moreover, Th17 cell signalling is likely to be a key factor in cardiovascular disease. Here, we summarize recent advances in the source, function, regulation, and the effects of Th17 signaling in cardiovascular disease. Research on Th17 will suggest more specific strategies to manipulate these functions. Thus, effective treatment of cardiovascular disease and future clinical treatment will be possible.
引用
收藏
页数：10
相关论文
共 50 条
  • [1] Signs of the presence of Th17 cells in chronic periodontal disease
    Adibrad, M.
    Deyhimi, P.
    Hakemi, M. Ganjalikhani
    Behfarnia, P.
    Shahabuei, M.
    Rafiee, L.
    JOURNAL OF PERIODONTAL RESEARCH, 2012, 47 (04) : 525 - 531
  • [2] Th17 cells in human disease
    Tesmer, Laura A.
    Lundy, Steven K.
    Sarkar, Sujata
    Fox, David A.
    IMMUNOLOGICAL REVIEWS, 2008, 223 : 87 - 113
  • [3] IL-17 and Th17 Cells in Atherosclerosis Subtle and Contextual Roles
    Taleb, Soraya
    Tedgui, Alain
    Mallat, Ziad
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2015, 35 (02) : 258 - 264
  • [4] Th17 cells in autoimmune demyelinating disease
    Benjamin Matthew Segal
    Seminars in Immunopathology, 2010, 32 : 71 - 77
  • [5] Th17 cells in autoimmune demyelinating disease
    Segal, Benjamin Matthew
    SEMINARS IN IMMUNOPATHOLOGY, 2010, 32 (01) : 71 - 77
  • [6] Th17 cells in systemic lupus erythematosus share functional features with Th17 cells from normal bone marrow and peripheral tissues
    Henriques, Ana
    Ines, Luis
    Pais, Maria Luisa
    Pereira da Silva, Jose Antonio
    Paiva, Artur Augusto
    CLINICAL RHEUMATOLOGY, 2012, 31 (03) : 483 - 491
  • [7] A High Frequency of Circulating Th22 and Th17 Cells in Patients with New Onset Graves' Disease
    Peng, Di
    Xu, Bingchuan
    Wang, Ye
    Guo, Hui
    Jiang, Yanfang
    PLOS ONE, 2013, 8 (07):
  • [8] Downregulation of Th17 cells and the related cytokines with treatment in Kawasaki disease
    Rasouli, Manoochehr
    Heidari, Behzad
    Kalani, Mehdi
    IMMUNOLOGY LETTERS, 2014, 162 (01) : 269 - 275
  • [9] Potential role of Th17 cells in the pathogenesis of adult-onset Still's disease
    Chen, Der-Yuan
    Chen, Yi-Ming
    Lan, Joung-Liang
    Lin, Chi-Chen
    Chen, Hsin-Hua
    Hsieh, Chia-Wei
    RHEUMATOLOGY, 2010, 49 (12) : 2305 - 2312
  • [10] Th17 Cytokines in Recall Responses Against Francisella Tularensis in Humans
    Paranavitana, Chrysanthi
    Zelazowska, Elzbieta
    DaSilva, Luis
    Pittman, Phillip R.
    Nikolich, Mikeljon
    JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, 2010, 30 (07) : 471 - 476
12345