Obstructive sleep apnea syndrome (OSAS) in women: A forgotten cardiovascular risk factor

被引：2

作者：

Moscucci, Federica ^{[1
,12
]}

Bucciarelli, Valentina ^{[2
]}

Gallina, Sabina ^{[3
]}

Sciomer, Susanna ^{[4
]}

Mattioli, Anna Vittoria ^{[5
]}

Maffei, Silvia ^{[6
]}

Nodari, Savina ^{[7
,8
]}

Pedrinelli, Roberto ^{[9
]}

Andreozzi, Paola ^{[10
]}

Basili, Stefania ^{[11
]}

Italian Soc Internal Med SIMI

机构：

[1] Azienda Osped Univ Policlin Umberto I, Dept Internal Med, Viale Policlin 155, I-00161 Rome, Italy

[2] Azienda Osped Univ Marche, Cardiovasc Sci Dept, I-60126 Ancona, Italy

[3] G Dannunzi Univ, Dept Neurosci Imaging & Clin Sci, Chieti, Italy

[4] Sapienza Univ Rome, Dept Clin & Internal Med Anesthesiol & Cardiovasc, Rome, Italy

[5] Univ Bologna, Dept Life Sci Qual, Bologna, Italy

[6] Fdn G Monasterio CNR Reg Toscana, Cardiovasc & Gynaecol Endocrinol Unit, Via G Moruzzi 1, I-56124 Pisa, Italy

[7] Univ Brescia, Dept Cardiol, I-25123 Brescia, Italy

[8] ASST Spedali Civili Hosp, I-25123 Brescia, Italy

[9] Univ Pisa, Cardiac Thorac & Vasc Dept, I-56126 Pisa, Italy

[10] Azienda Osped Univ Policlin Umberto 1, Dept Internal Med Endocrine Metab Sci & Infect Dis, Predict Med Gender Specif & Chron Unit, SIMI Natl Direct, Rome, Italy

[11] Sapienza Univ Rome, Dept Translat & Precis Med, Viale Policlin 155, I-00161 Rome, Italy

[12] Univ Aquila, Dept Clin Med, I-67100 Laquila, Italy

来源：

MATURITAS | 2025年 / 193卷

关键词：

Sleep apnea; Sleep-disordered breathing; Women; Gender; Cardiovascular risk factor; POSITIVE AIRWAY PRESSURE; POLYCYSTIC-OVARY-SYNDROME; SEX-DIFFERENCES; RESISTANT HYPERTENSION; GENERAL-POPULATION; ASSOCIATION; PREVALENCE; GENDER; MANAGEMENT; IMPACT;

D O I：

10.1016/j.maturitas.2024.108170

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Sleep-disordered breathing is a highly prevalent disorder with negative impact on healthcare systems worldwide. This condition has detrimental effects on cardiovascular health and quality of life, and is frequently associated with a variety of comorbidities, including cardiovascular disease, heart failure, diabetes and atrial fibrillation. Nevertheless, it remains frequently undiagnosed and undertreated, especially in specific populations. Studies on sleep-disordered breathing have been conducted mainly on male patients, and the prevalence and severity of this disorder in women are underestimated. Recently, some clinical and laboratory evidence has highlighted the epidemiological and pathophysiological differences between men and women with sleep-disordered breathing. In this review, we discuss sex-related mechanisms of sleep-disordered breathing in frequently associated disorders, to improve clinical understanding of this condition and to simplify the practical application of targeted interventions. The aim is to improve prognosis among female patients and guarantee a better quality of life and a reduction in healthcare costs.

引用

页数：12

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