Impact of Transoral Robotic Surgery Versus Radiation on Swallowing Function in Oropharyngeal Cancer Patients: A Sub-Study From a Randomized Trial

被引：1
|
作者：
Theurer, Julie. A. [1 ,2 ,3 ]
Martino, Rosemary [2 ,4 ,5 ,6 ]
Jovanovic, Nedeljko [2 ]
de Almeida, John R. [5 ]
Goldstein, David P. [5 ]
Fung, Kevin [2 ]
Yoo, John [2 ]
Macneil, S. Danielle [2 ]
Winquist, Eric [7 ]
Hammond, J. Alex [8 ]
Venkatesan, Varagur [8 ]
Read, Nancy [8 ]
Kuruvilla, Sarah [7 ]
Warner, Andrew [8 ]
Doyle, Philip C. [9 ]
Ross, Ian [10 ]
Dreyer, Colleen [11 ]
Hawkins, Sarah [11 ]
Thouless, Kendra [11 ]
McCallum, Courtney [12 ]
Palma, David A. [8 ]
Nichols, Anthony C. [2 ]
机构：
[1] Western Univ, Sch Commun Sci & Disorders, London, ON, Canada
[2] Western Univ, Dept Otolaryngol Head & Neck Surg, London, ON, Canada
[3] Lawson Hlth Res Inst, London, ON, Canada
[4] Univ Toronto, Dept Speech Language Pathol, Toronto, ON, Canada
[5] Univ Toronto, Dept Otolaryngol Head & Neck Surg, Toronto, ON, Canada
[6] Univ Hlth Network, Krembil Res Inst, Toronto, ON, Canada
[7] Western Univ, Dept Med Biophys, London, ON, Canada
[8] Western Univ, Oncol, London, ON, Canada
[9] Stanford Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, Div Laryngol, Stanford, CA USA
[10] Western Univ, Dept Radiol, London, ON, Canada
[11] London Hlth Sci Ctr, Dept Speech Language Pathol, London, ON, Canada
[12] Western Univ, Hlth & Rehabil Sci, London, ON, Canada
来源：
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2025年 / 47卷 / 03期
关键词：
ORATOR; oropharyngeal cancer; radiotherapy; swallowing physiology; transoral robotic surgery; SQUAMOUS-CELL CARCINOMA; QUALITY-OF-LIFE; NECK-CANCER; HEAD; DYSPHAGIA; RADIOTHERAPY; OUTCOMES; CHEMOTHERAPY; CHEMORADIATION; ASPIRATION;
D O I：
10.1002/hed.27986
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
BackgroundThis ORATOR sub-study evaluated swallowing physiology in patients treated with transoral robotic surgery (TORS) versus radiotherapy (RT) for early-stage oropharynx cancer.MethodsSwallowing physiology was evaluated using videofluoroscopy and outcomes were compared across treatment arms and correlated with MDADI scores.ResultsOf the 68 patients in the ORATOR trial, 21 participated in this sub-study (30.8%), including 15 RT Arm and six TORS Arm patients. Swallowing profiles were not significantly different between the arms. MBSImP pharyngeal scores for RT Arm versus TORS Arm patients were 4.8 (+/- 2.1) versus 4.3 (+/- 1.5) at baseline, 6.2 (+/- 1.2) versus 9.6 (+/- 4.8) at 6 months and 5.9 (+/- 1.8) versus 8.0 (+/- 4.7) at 12 months. MBSImP pharyngeal scores demonstrated weak associations with several MDADI subscales and PAS scores.ConclusionsTo best describe swallowing outcomes in studies of RT and/or surgery, instrumental swallowing assessments should be strongly considered in addition to quality of life measures.
引用
收藏
页码：906 / 916
页数：11
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