Pediatric Opioid-Use-Associated Neurotoxicity with Cerebellar Edema: A Case of POUNCE Syndrome Following Vein of Galen Aneurysm Treatment

被引:0
作者
Goldfinger, Maxime [1 ]
机构
[1] Chu Brugmann, Brussels, Belgium
关键词
POUNCE syndrome; pediatric neurotoxicity; cerebellar edema; opioid-induced encephalopathy;
D O I
10.5334/jbsr.3786
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
We report the case of a 4-year-old child who experienced rapid neurological decline following opioid administration during anesthesia for an interventional procedure to treat a vein of Galen aneurysm. Cerebral magnetic resonance imaging (MRI) revealed marked cytotoxic edema in both cerebellar hemispheres and the brainstem, indicative of opioid-induced neurotoxicity. A follow-up MRI, performed 2 weeks later, showed profound cerebellar and brainstem atrophy and showed reduction in mass effect due to cytotoxic edema. Teaching point: Pediatric opioid-use-associated neurotoxicity with cerebellar edema (POUNCE) syndrome is a rare condition, characterized by cerebellar edema as a hallmark feature, which can be identified on MRI in pediatric patients following opioid use.
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页数:4
相关论文
共 3 条
[1]   Malignant Cerebellar Edema Subsequent to Accidental Prescription Opioid Intoxication in Children [J].
Duran, Daniel ;
Messina, Robert D. ;
Beslow, Lauren A. ;
Montejo, Julio D. ;
Karimy, Jason K. ;
Furey, Charuta Gavankar ;
Sheridan, Alison D. ;
Sze, Gordon ;
Yarman, Yanki ;
DiLuna, Michael L. ;
Kahle, Kristopher T. .
FRONTIERS IN NEUROLOGY, 2017, 8
[2]   Clinical and radiologic features of pediatric opioid use-associated neurotoxicity with cerebellar edema (POUNCE) syndrome [J].
Kim, David Dongkyung ;
Prasad, Asuri Narayan .
NEUROLOGY, 2020, 94 (16) :710-712
[3]  
Potluri A, 2024, NEUROLOGY, V102, DOI [10.1212/wnl.0000000000206232, 10.1212/WNL.0000000000206232, DOI 10.1212/WNL.0000000000206232]