A Rare Case of Functional Metastatic Follicular Thyroid Carcinoma With Concomitant Thyrotoxicosis

被引：0

作者：

Chin, Yun Ann ^{[1
]}

Sumbul, Zaheer ^{[2
]}

Teh, Yi Lin ^{[3
]}

Chng, Chiaw Ling ^{[1
]}

机构：

[1] Singapore Gen Hosp, Dept Endocrinol, Singapore, Singapore

[2] Singapore Gen Hosp, Dept Nucl Med & Mol Imaging, Singapore, Singapore

[3] Natl Canc Ctr Singapore, Dept Med Oncol, Singapore, Singapore

来源：

CASE REPORTS IN ENDOCRINOLOGY | 2024年 / 2024卷 / 01期

关键词：

Graves' disease; metastatic follicular thyroid carcinoma; radioiodine treatment; thyroid stimulating hormone receptor antibody; thyroidectomy; GRAVES-DISEASE; CANCER;

D O I：

10.1155/crie/1398125

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report a case of a 60-year-old lady with metastatic follicular thyroid carcinoma (FTC) who was presented with thyrotoxicosis and heart failure symptoms after total thyroidectomy. Clinical features and investigations led to the diagnosis of functional metastatic FTC with concomitant thyrotoxicosis. Levothyroxine therapy was stopped, and she was treated with propylthiouracil (PTU) followed by serial radioiodine treatments (RAITs) with good control of thyrotoxicosis and metastases. Despite having a very high disease burden with metastatic FTC, she has been able to maintain her functional status thus far, 4.5 years after initial diagnosis.

引用

页数：8

共 15 条

[1] A case of metastatic follicular thyroid carcinoma complicated with Graves' disease after total thyroidectomy [J].

Aoyama, Mariko ;

Takizawa, Hiromitsu ;

Tsuboi, Mitsuhiro ;

Nakagawa, Yasushi ;

Tangoku, Akira .

ENDOCRINE JOURNAL, 2017, 64 (12) :1143-1147

[2] Treatment and outcome of patients with Graves' disease and metastatic differentiated thyroid cancer [J].

Besic, Nikola ;

Vidergar-Kralj, Barbara .

RADIOLOGY AND ONCOLOGY, 2023, 57 (03) :380-388

[3] THYROTOXICOSIS ASSOCIATED WITH DISTANT METASTATIC FOLLICULAR CARCINOMA OF THE THYROID [J].

BOWDEN, WD ;

JONES, RE .

SOUTHERN MEDICAL JOURNAL, 1986, 79 (04) :483-486

[4]

Geliebter A, 2017, J ENDOCR SOC, V1, P1440, DOI 10.1210/js.2017-00296

[5]

Haq M, 2007, Br J Radiol, V80, pe38, DOI 10.1259/bjr/52032397

[6] 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer [J].

Haugen, Bryan R. ;

Alexander, Erik K. ;

Bible, Keith C. ;

Doherty, Gerard M. ;

Mandel, Susan J. ;

Nikiforov, Yuri E. ;

Pacini, Furio ;

Randolph, Gregory W. ;

Sawka, Anna M. ;

Schlumberger, Martin ;

Schuff, Kathryn G. ;

Sherman, Steven I. ;

Sosa, Julie Ann ;

Steward, David L. ;

Tuttle, R. Michael ;

Wartofsky, Leonard .

THYROID, 2016, 26 (01) :1-133

[7]

Kojima-Ishii Kanako, 2014, Clin Pediatr Endocrinol, V23, P59, DOI 10.1297/cpe.23.59

[8] De Novo Extra-Thyroidal Manifestations of Graves' Disease presenting 16 Years after Total Thyroidectomy for Thyroid Cancer [J].

Kwee, Ann ;

Yong, Kai-Ling ;

Seah, Lay Leng ;

Ching, Chiaw-Ling .

JOURNAL OF THE ASEAN FEDERATION OF ENDOCRINE SOCIETIES, 2021, 36 (02) :216-219

[9] Hyperfunctioning thyroid carcinoma: A systematic review [J].

Liu, Jun ;

Wang, Ye ;

Da, Dongzhu ;

Zheng, Miao .

MOLECULAR AND CLINICAL ONCOLOGY, 2019, 11 (06) :535-550

[10] THYROTOXICOSIS CAUSED BY THYROID-CANCER [J].

PAUL, SJ ;

SISSON, JC .

ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA, 1990, 19 (03) :593-612

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