A second chance for avatrombopag in chemotherapy-induced thrombocytopenia

被引:0
作者
Al-Samkari, Hanny [1 ,2 ]
Moore, Donald C. [3 ]
机构
[1] Massachusetts Gen Hosp, Div Hematol Oncol, Bartlett Hall Extens Off 133, Boston, MA 02114 USA
[2] Harvard Med Sch, Boston, MA USA
[3] Atrium Hlth, Levine Canc Inst, Dept Pharm, Charlotte, NC USA
关键词
avatrombopag; chemotherapy-induced thrombocytopenia; persistent; romiplostim; thrombopoietin receptor agonist; ROMIPLOSTIM;
D O I
10.1111/bjh.19861
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Chemotherapy-induced thrombocytopenia (CIT) remains a common complication of cancer therapy with no approved available treatments in most of the world. Although a prior clinical trial of avatrombopag for CIT did not meet its primary end-point, a report from Galamaga and colleagues raises prospects for a second chance for avatrombopag in CIT, highlighting the differences between nadir and persistent CIT and the importance of patient selection in CIT treatment.
引用
收藏
页码:375 / 377
页数:3
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