Comparative efficacy of traditional non-pharmacological add-on treatments in patients with stable chronic obstructive pulmonary disease: a systematic review and network meta-analysis

被引：0

作者：

Roh, Ji-Ae ^{[1
,2
]}

Leem, Jungtae ^{[3
,4
]}

Lee, Beom-Joon ^{[1
,2
]}

Kim, Kwan-Il ^{[1
,2
]}

Jung, Hee-Jae ^{[1
,2
]}

机构：

[1] Kyung Hee Univ, Coll Korean Med, Grad Sch, Dept Clin Korean Med, Seoul, South Korea

[2] Kyung Hee Univ, Med Ctr, Coll Korean Med, Dept Internal Med,Div Allergy Immune & Resp Syst, Seoul, South Korea

[3] Wonkwang Univ, Coll Korean Med, Dept Diagnost, Iksan, South Korea

[4] Wonkwang Univ, Korean Med Hosp, Dept Ilwon Integrated Med, Iksan, South Korea

来源：

FRONTIERS IN PUBLIC HEALTH | 2025年 / 13卷

关键词：

chronic obstructive pulmonary disease; non-pharmacological treatment; AddOn; systematic review; network meta-analysis; RESPIRATORY MUSCLE STRENGTH; BETA-ENDORPHIN LEVEL; QUALITY-OF-LIFE; TAI-CHI; ACU-TENS; EXERCISE CAPACITY; LIUZIJUE EXERCISE; ELDERLY-PATIENTS; MANUAL THERAPY; LUNG-FUNCTION;

D O I：

10.3389/fpubh.2025.1410342

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Chronic obstructive pulmonary disease (COPD) is a major global public health concern. In this study, we examined the comparative efficacy of non-pharmacological interventions within East Asian traditional medicine (EATM-NPI) for enhancing pulmonary function and exercise capacity in patients with stable COPD. A thorough search of electronic databases conducted until May 22, 2022, identified studies employing EATM-NPI in such patients. The evaluation focused on the impact adjunctive therapies on pulmonary function (forced expiratory volume in 1 s [FEV1]) and exercise capacity (6-min walking distance [6MWD]). The qualitative assessment encompassed 142 studies, with 133 studies included in one of three network meta-analyses. Participants, aged 49-76 years, ranged from 9 to 139 per group, predominantly from China (87.7% of studies). Overall study quality was generally low, and reported adverse events were mild. Notably, moxibustion and qigong adjunctive therapies demonstrated significant improvements in FEV1 (L) and FEV1 (%). Additionally, chuna, acupuncture, qigong and moxibustion adjunctive therapies were associated with significant improvements in 6MWD. In conclusion, EATM-NPI adjunctive therapy, when combined with standard pharmacological treatment, exhibited effects on pulmonary function and exercise capacity in patients with COPD. Systematic review registration: The protocol was registered with PROSPERO (CRD42023389431), https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023389431.

引用

页数：31