A Portable Zn2+ Fluorescence Sensor for Information Storage and Bio-Imaging in Living Cells

被引：1

作者：

Li, Xiujuan ^{[1
,2
]}

Gao, Tinghuan ^{[1
]}

Wang, Shoucheng ^{[2
]}

Zhang, Qing ^{[1
]}

Chen, Siyu ^{[1
]}

Zhang, Hongshuo ^{[1
]}

Xu, Jinbin ^{[1
]}

Wang, Xinchao ^{[1
,3
]}

Liu, Qianqian ^{[1
]}

机构：

[1] Heze Univ, Heze 274015, Shangdong, Peoples R China

[2] Heze Vocat Coll, Heze 274015, Shangdong, Peoples R China

[3] Key Lab Targeted Diag & Treatment Canc Dis Heze, Heze 274015, Shangdong, Peoples R China

来源：

JOURNAL OF FLUORESCENCE | 2024年

关键词：

Zn2+; Fluorescent probe; Designed and synthesized; Application; SELECTIVE DETECTION; SCHIFF-BASE; PROBE; ZN(II); CHEMOSENSOR; RECOGNITION; ION;

D O I：

10.1007/s10895-024-04018-8

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A fluorescence probe (Probe-ITR) was designed and synthesized for the rapid detection of Zn2+ based on the excited state intramolecular proton transfer (ESIPT) mechanism. The specific recognition ability of Probe-ITR to Zn2+ was tested using UV-VIS and fluorescence emission spectroscopy. The results demonstrated a rapid response within 40s upon addition of an appropriate amount of Zn2+ into the mixed solution of the target probe molecules (DMSO/PBS = 5/5). Under 365 nm ultraviolet light irradiation, the colorless solution changed to yellow-green fluorescence with a 150-folds increase in intensity. Furthermore, the detection limit for specific recognition of Zn2+ by the probe molecule is only 17.3 nmol/L, indicating high sensitivity. The practical application potential of the probe molecules was enhanced by employing on information storage and conducting cell imaging experiments.

引用

页数：8

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