Pulsed dye laser-activated photodynamic therapy for extramammary Paget disease

Extramammary Paget disease of the skin (EMPD) is a rare malignant dermatological condition with metastatic potential, characteristically affecting the axillae, genitalia or perineum. Standard treatment is staged surgical excision. However, this treatment can prove challenging, particularly in extensive disease, and recurrence rates are high. Patient factors may also mean that they are not suitable for surgery. We describe the first reported case of successful pulsed dye laser-activated photodynamic therapy for EMPD. While further study is essential, we present this case report as a contribution to the body of evidence of treatments that may be effective in managing this condition.