Natural polymer nanofiber dressings for effective management of chronic diabetic wounds: A comprehensive review

被引：10
作者：
Zhou, Zhengqing [1 ]
Li, Chaofei [2 ]
Zeng, Yue [3 ]
Huang, Tianyue [1 ]
Jiang, Xuewen [1 ]
Yu, Deng-Guang [1 ]
Wang, Ke [1 ]
机构：
[1] Univ Shanghai Sci & Technol, Sch Mat & Chem, 516 Jungong Rd, Shanghai 200093, Peoples R China
[2] Shanghai Jiao Tong Univ, RuiJin Hosp,Lu Wan Branch, Dept Gen Surg, Sch Med, Shanghai 200020, Peoples R China
[3] Shanghai Jiao Tong Univ, RuiJin Hosp,Lu Wan Branch, Dept Urol, Sch Med, Shanghai, Peoples R China
来源：
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2024年 / 282卷
关键词：
Natural polymers; Diabetic wounds; Electrospinning nanofiber dressings; SILK FIBROIN NANOFIBERS; DRUG-DELIVERY-SYSTEMS; ANTIBACTERIAL ACTIVITY; ESSENTIAL OILS; ELECTROSPUN NANOFIBERS; ANTIMICROBIAL ACTIVITY; COMPOSITE NANOFIBERS; SILVER NANOPARTICLES; IN-VITRO; CHITOSAN;
D O I：
10.1016/j.ijbiomac.2024.136688
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Diabetic wounds present a chronic challenge in effective treatment. Natural polymer nanofiber dressings have emerged as a promising solution due to their impressive biocompatibility, biodegradability, safety, high specific surface area, and resemblance to the extracellular matrix. These qualities make them ideal materials with excellent biological properties and cost-effectiveness. Additionally, they can effectively deliver therapeutic agents, enabling diverse treatment effects. This review offers a comprehensive overview of natural polymerbased nanofibers in diabetic wound dressings. It examines the characteristics and challenges associated with diabetic wounds and the role of natural polymers in facilitating wound healing. The review highlights the preparation, mechanism, and applications of various functional dressings composed of natural polymer nanofibers. Furthermore, it addresses the main challenges and future directions in utilizing natural polymer nanofibers for diabetic wound treatment, providing valuable insights into effective wound management for diabetic patients.
引用
收藏
页数：25
相关论文
共 265 条
[1]   RETRACTED: Antimicrobial and antioxidant properties of chitosan and its derivatives and their applications: A review (Retracted article. See vol. 293, 2025) [J].
Abd El-Hack, Mohamed E. ;
El-Saadony, Mohamed T. ;
Shafi, Manal E. ;
Zabermawi, Nidal M. ;
Arif, Muhammad ;
Batiha, Gaber Elsaber ;
Khafaga, Asmaa F. ;
Abd El-Hakim, Yasmina M. ;
Al-Sagheer, Adham A. .
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 164 :2726-2744
[2]  
Abdelaal A, 2021, QJM-INT J MED, V114, DOI [10.1093/qjmed/hcab097.040, 10.1093/qjmed/hcab097.040, DOI 10.1093/QJMED/HCAB097.040]
[3]   Novel electrospun chitosan/polyvinyl alcohol/zinc oxide nanofibrous mats with antibacterial and antioxidant properties for diabetic wound healing [J].
Ahmed, Rashid ;
Tariq, Muhammad ;
Ali, Imran ;
Asghar, Rehana ;
Khanam, P. Noorunnisa ;
Augustine, Robin ;
Hasan, Anwarul .
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 120 :385-393
[4]   Antioxidant Phytochemicals as Potential Therapy for Diabetic Complications [J].
Akpoveso, Oke-Oghene Philomena ;
Ubah, Emeka Emmanuel ;
Obasanmi, Gideon .
ANTIOXIDANTS, 2023, 12 (01)
[5]   Antimicrobial and Wound Healing Performance of Polycaprolactone Electrospun-Based Nanofibers Incorporating Propolis and Quercus Infectoria Gall Extracts [J].
Aliee, Faezeh ;
Fahimirad, Shohreh ;
Ganji, Ali ;
Abtahi, Hamid .
NANO, 2025, 20 (01)
[6]   Nanofibrous Scaffolds for Diabetic Wound Healing [J].
Aliyu, Anna Yusuf ;
Adeleke, Oluwatoyin A. .
PHARMACEUTICS, 2023, 15 (03)
[7]   PDGF and VEGF-releasing bi-layer wound dressing made of sodium tripolyphosphate crosslinked gelatin-sponge layer and a carrageenan nanofiber layer [J].
Alizadeh, Mansoor ;
Salehi, Saeideh ;
Tavakoli, Mohamadreza ;
Mirhaj, Marjan ;
Varshosaz, Jaleh ;
Kazemi, Nafise ;
Salehi, Sepideh ;
Mehrjoo, Morteza ;
Abadi, Shaghayegh Amini Mosleh .
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2023, 233
[8]   Multifunctional Biomimetic Nanofibrous Scaffold Loaded with Asiaticoside for Rapid Diabetic Wound Healing [J].
Anand, Sneha ;
Rajinikanth, Paruvathanahalli Siddalingam ;
Arya, Dilip Kumar ;
Pandey, Prashant ;
Gupta, Ravi K. ;
Sankhwar, Ruchi ;
Chidambaram, Kumarappan .
PHARMACEUTICS, 2022, 14 (02)
[9]   A focused review on hyaluronic acid contained nanofiber formulations for diabetic wound healing [J].
Astaneh, Mohammad Ebrahim ;
Fereydouni, Narges .
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2023, 253
[10]   Nanofiber technology: Designing the next generation of tissue engineering scaffolds [J].
Barnes, Catherine P. ;
Sell, Scott A. ;
Boland, Eugene D. ;
Simpson, David G. ;
Bowlin, Gary L. .
ADVANCED DRUG DELIVERY REVIEWS, 2007, 59 (14) :1413-1433
12345678910