Targeting Mitochondrial Metabolism to Promote Viral Mimicry and Type I Interferon Response in Acute Myeloid Leukemia

被引：0
作者：
Balasundaram, Nithya [1 ]
Andreas, Hernan Tirado [1 ]
Leguay, Fleur [1 ]
Van Gastel, Nick [1 ]
机构：
[1] UC Louvain, De Duve Inst, Lab Cellular Metab & Microenvironm, Brussels, Belgium
来源：
BLOOD | 2024年 / 144卷
关键词：
D O I：
10.1182/blood-2024-210257
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：827 / 828
页数：2
相关论文
共 50 条
  • [41] Targeting Mitochondrial Translation Overcomes Venetoclax Resistance in Acute Myeloid Leukemia (AML) through Activation of the Integrated Stress Response
    Sharon, David
    Cathelin, Severine
    Subedi, Amit
    Williams, Ryan
    Benicio, Mariana
    Ketela, Troy
    Chan, Steven M.
    BLOOD, 2017, 130
  • [42] Targeting Mitochondrial Apoptotic Priming State to Personalize Therapy for Relapsed Acute Myeloid Leukemia
    Olesinski, Elyse
    Bhatia, Karanpreet
    Wang, Chuqi
    Pioso, Marissa
    Ng, Shu Xuan
    Lin, Xiao Xian
    Sandhu, Vedant
    Yilma, Binyam
    Bohl, Stephan Rainer Maximilian
    Ryan, Jeremy
    Malani, Disha
    Luskin, Marlise R.
    Kallioniemi, Olli
    Porkka, Kimmo
    Yeoh, Allen
    Adamia, Sophia
    Chng, Wee Joo
    Osato, Motomi
    Weinstock, David M.
    Garcia, Jacqueline S.
    Letai, Anthony G.
    Bhatt, Shruti
    BLOOD, 2023, 142
  • [43] Targeting the Mammalian Mitochondrial Clpp (mClpP) As a Novel Therapeutic Strategy for Acute Myeloid Leukemia
    Cole, Alicia
    Wang, Zezhou
    Mattson, Rachel
    Hurren, Rose
    Lin, Fengshu
    Gronda, Marcela
    Maclean, Neil
    Isaac, Methvin
    Leung, Elisa
    Babu, Mohan
    Sukhai, Mahadeo A.
    Houry, Walid A.
    Schimmer, Aaron D.
    BLOOD, 2012, 120 (21)
  • [44] Modelling dynamics of the type I interferon response to in vitro viral infection
    Howat, Tom J.
    Barreca, Cristina
    O'Hare, Peter
    Gog, Julia R.
    Grenfell, Bryan T.
    JOURNAL OF THE ROYAL SOCIETY INTERFACE, 2006, 3 (10) : 699 - 709
  • [45] The type I interferon response during viral infections: a "SWOT" analysis
    Gaajetaan, Giel R.
    Bruggeman, Cathrien A.
    Stassen, Frank R.
    REVIEWS IN MEDICAL VIROLOGY, 2012, 22 (02) : 122 - 137
  • [46] Induction and function of type I and III interferon in response to viral infection
    Levy, David E.
    Marie, Isabelle J.
    Durbin, Joan E.
    CURRENT OPINION IN VIROLOGY, 2011, 1 (06) : 476 - 486
  • [47] Integrated bioinformatic analysis of mitochondrial metabolism-related genes in acute myeloid leukemia
    Tong, Xiqin
    Zhou, Fuling
    FRONTIERS IN IMMUNOLOGY, 2023, 14
  • [48] Mitochondrial Profiling of Acute Myeloid Leukemia in the Assessment of Response to Apoptosis Modulating Drugs
    Ishizawa, Jo
    Kojima, Kensuke
    McQueen, Teresa
    Ruvolo, Vivian
    Chachad, Dhruv
    Nogueras-Gonzalez, Graciela M.
    Huang, Xuelin
    Pierceall, William E.
    Dettman, E. J.
    Cardone, Michael H.
    Shacham, Sharon
    Konopleva, Marina
    Andreeff, Michael
    PLOS ONE, 2015, 10 (09):
  • [49] Acute hepatitis A virus infection is associated with a limited type I interferon response and persistence of intrahepatic viral RNA
    Lanford, Robert E.
    Feng, Zongdi
    Chavez, Deborah
    Guerra, Bernadette
    Brasky, Kathleen M.
    Zhou, Yan
    Yamane, Daisuke
    Perelson, Alan S.
    Walker, Christopher M.
    Lemon, Stanley M.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (27) : 11223 - 11228
  • [50] Therapeutic Targeting of Ferroptosis Pathway in Combination with Mitochondrial Oxidative Stress Induction in Acute Myeloid Leukemia
    Akiyama, Hiroki
    Zhao, Ran
    Rahhal, Adam
    Nishida, Yuki
    Ayoub, Edward
    BOstermann, Lauren
    Andreeff, Michael
    Ishizawa, Jo
    BLOOD, 2021, 138
12345