Hyperthyroidism-induced myocardial infarction: a case of coronary spasm

Background: In the etiology of coronary artery spasm (CAS), elevated thyroid hormone levels have been implicated, disrupting cardiac homeostasis and precipitating acute myocardial infarction (AMI). We report a case of AMI secondary to CAS in a male with hyperthyroidism without other classical cardiovascular risk factors. Case Description: A 48-year-old male with a known history of hyperthyroidism but no other known classical cardiovascular risk factor urgently attended the hospital with suggestive symptoms of an AMI. The diagnostic process revealed CAS; he was managed successfully with intracoronary nitrates. We noted his elevated thyroid hormone levels, thus linking the hyperthyroid state to the CAS and subsequent AMI. Conclusion: The reported case highlights the diagnostic complexities in patients suffering from hyperthyroidism and presenting with atypical AMI and emphasizes the importance of thyroid function evaluation in such cases. The management includes treatment of the AMI and long-term normalization of the thyroid function, and this case emphasizes the critical interaction between these conditions, advocating for a multidisciplinary approach to managing atypical coronary events in the context of underlying endocrine disorders. HIPPOKRATIA 2024, 28 (3):126-128.