Systemic therapy for Child-Pugh B patients with hepatocellular carcinoma

被引:0
作者
Mok, Kevin [1 ]
Chen, Olivia [1 ]
Yau, Johnny [1 ]
Chan, Landon L. [2 ]
Chan, Stephen L. [1 ,2 ]
机构
[1] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Clin Oncol, Shatin, 30-32 Ngan Shing St, Hong Kong, Peoples R China
[2] Chinese Univ Hong Kong, Hong Kong Canc Inst, Sir YK Pao Ctr Canc, Dept Clin Oncol,State Key Lab Translat Oncol, Hong Kong, Peoples R China
关键词
Child-Pugh B; hepatocellular carcinoma; immune-checkpoint inhibitors; immunotherapy; liver cancer; targeted therapy; systemic therapy; CLINICAL-PRACTICE; CIRRHOSIS; SAFETY;
D O I
10.1080/14728214.2025.2456774
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:1 / 5
页数:5
相关论文
共 32 条
[1]   Clinical outcomes by Child-Pugh Class in patients with advanced hepatocellular carcinoma in a community oncology setting [J].
Aly, Abdalla ;
Fulcher, Nicole ;
Seal, Brian ;
Pham, Trang ;
Wang, Yunfei ;
Paulson, Scott ;
He, Aiwu R. .
HEPATIC ONCOLOGY, 2023, 10 (01)
[2]   Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries [J].
Bray, Freddie ;
Laversanne, Mathieu ;
Sung, Hyuna ;
Ferlay, Jacques ;
Siegel, Rebecca L. ;
Soerjomataram, Isabelle ;
Jemal, Ahmedin .
CA-A CANCER JOURNAL FOR CLINICIANS, 2024, 74 (03) :229-263
[3]   Early Hepatic Decompensation Identifies Patients with Hepatocellular Carcinoma Treated with Atezolizumab plus Bevacizumab or Sorafenib at Highest Risk of Death [J].
Cabibbo, Giuseppe ;
Celsa, Ciro ;
Battaglia, Salvatore ;
Enea, Marco ;
Di Maria, Gabriele ;
Grova, Alessandro ;
Ciccia, Roberta ;
Manfredi, Giulia F. ;
Iavarone, Massimo ;
Vogel, Arndt ;
Singal, Amit G. ;
Reig, Maria ;
Pinato, David J. ;
Camma, Calogero .
CLINICAL CANCER RESEARCH, 2025, 31 (03) :543-550
[4]   Navigating the landscape of liver cancer management: Study designs in clinical trials and clinical practice [J].
Cabibbo, Giuseppe ;
Celsa, Ciro ;
Rimassa, Lorenza ;
Torres, Ferran ;
Rimola, Jordi ;
Kloeckner, Roman ;
Bruix, Jordi ;
Camma, Calogero ;
Reig, Maria .
JOURNAL OF HEPATOLOGY, 2024, 80 (06) :957-966
[5]   SIERRA: A phase IIIb, single-arm, multicentre study of tremelimumab plus durvalumab for first-line treatment of advanced unresectable hepatocellular carcinoma [J].
Chan, S. L. ;
Sangro, B. ;
Kudo, M. ;
Dane, A. ;
Emery, C. ;
Paskow, M. ;
Makowsky, M. ;
Nguyen, B. ;
Rimassa, L. .
ANNALS OF ONCOLOGY, 2023, 34 :S1554-S1554
[6]   Comparison of nivolumab and sorafenib for first systemic therapy in patients with hepatocellular carcinoma and Child-Pugh B cirrhosis [J].
Chapin, William J. ;
Hwang, Wei-Ting ;
Karasic, Thomas B. ;
McCarthy, Anne Marie ;
Kaplan, David E. .
CANCER MEDICINE, 2023, 12 (01) :189-199
[7]   Atezolizumab plus bevacizumab in patients with child-Pugh B advanced hepatocellular carcinoma [J].
Cheon, Jaekyung ;
Kim, Hyeyeong ;
Kim, Han Sang ;
Kim, Chang Gon ;
Kim, Ilhwan ;
Kang, Beodeul ;
Kim, Chan ;
Jung, Sanghoon ;
Ha, Yeonjung ;
Chon, Hong Jae .
THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY, 2023, 15
[8]   Preliminary evidence of safety and tolerability of atezolizumab plus bevacizumab in patients with hepatocellular carcinoma and Child-Pugh A and B cirrhosis: A real-world study [J].
D'Alessio, Antonio ;
Fulgenzi, Claudia Angela Maria ;
Nishida, Naoshi ;
Schoenlein, Martin ;
von Felden, Johann ;
Schulze, Kornelius ;
Wege, Henning ;
Gaillard, Vincent E. ;
Saeed, Anwaar ;
Wietharn, Brooke ;
Hildebrand, Hannah ;
Wu, Linda ;
Ang, Celina ;
Marron, Thomas U. ;
Weinmann, Arndt ;
Galle, Peter R. ;
Bettinger, Dominik ;
Bengsch, Bertram ;
Vogel, Arndt ;
Balcar, Lorenz ;
Scheiner, Bernhard ;
Lee, Pei-Chang ;
Huang, Yi-Hsiang ;
Amara, Suneetha ;
Muzaffar, Mahvish ;
Naqash, Abdul Rafeh ;
Cammarota, Antonella ;
Personeni, Nicola ;
Pressiani, Tiziana ;
Sharma, Rohini ;
Pinter, Matthias ;
Cortellini, Alessio ;
Kudo, Masatoshi ;
Rimassa, Lorenza ;
Pinato, David J. .
HEPATOLOGY, 2022, 76 (04) :1000-1012
[9]   BOOST: a phase 3 trial of sorafenib vs. best supportive care in first line treatment of hepatocellular carcinoma in patients with deteriorated liver function [J].
Daniele, Gennaro ;
Schettino, Clorinda ;
Arenare, Laura ;
Bilancia, Domenico ;
Farinati, Fabio ;
Federico, Piera ;
Tamberi, Stefano ;
Crivellari, Gino ;
Barni, Sandro ;
Tortora, Raffaella ;
Izzo, Francesco ;
Frassoldati, Antonio ;
Cavanna, Luigi ;
Mucciarini, Claudia ;
Bolondi, Luigi ;
Dinota, Angelo ;
Pelizzaro, Filippo ;
Piccirillo, Maria Carmela ;
Gargiulo, Piera ;
Di Maio, Massimo ;
Gallo, Ciro ;
Perrone, Francesco ;
Daniele, Bruno .
HEPATOMA RESEARCH, 2021, 7
[10]   Safety and efficacy of cabozantinib for patients with advanced hepatocellular carcinoma who advanced to Child-Pugh B liver function at study week 8: a retrospective analysis of the CELESTIAL randomised controlled trial [J].
El-Khoueiry, Anthony B. ;
Meyer, Tim ;
Cheng, Ann-Lii ;
Rimassa, Lorenza ;
Sen, Suvajit ;
Milwee, Steven ;
Kelley, Robin Kate ;
Abou-Alfa, Ghassan K. .
BMC CANCER, 2022, 22 (01)