The Dallas Donation after Circulatory Death Transplantation Summit: expanding donation after circulatory death procedures through process improvement, broader utilization, and innovation

被引:0
作者
Finotti, Michele [1 ,2 ]
Wall, Anji
D'Alessandro, Anthony [3 ]
Schwartz, Gary [4 ]
Sonnenday, Chris [5 ]
Goldberg, David [6 ]
Shah, Ashish [7 ]
Friend, Peter [8 ]
Orlowski, Jeff P. [9 ]
Mckenna, Greg
Newton, Steve [10 ]
Adams, Brad [11 ]
Chapman, William C. [12 ]
Mathur, Amit [13 ]
Abouljoud, Marwan [14 ]
Pruett, Tim [15 ]
Hessheimer, Amelia [16 ]
Trotter, James F.
Asrani, Sumeet K. [1 ]
Testa, Giuliano
机构
[1] Baylor Univ Med Ctr, Simmons Transplant Inst, 3500 Gaston Ave, Dallas, TX 75246 USA
[2] Univ Padua, Reg Hosp Treviso, Hepatobiliary & Gen Surg Unit, DISCOG, Padua, Italy
[3] Univ Wisconsin, Dept Surg, Div Transplantat, Sch Med & Publ Hlth, Madison, WI USA
[4] Baylor Univ Med Ctr, Ctr Adv Heart & Lung Dis, Dept Thorac Surg & Lung Transplantat, Dallas, TX USA
[5] Univ Michigan, Dept Surg, Ann Arbor, MI USA
[6] Univ Miami, Dept Med, Div Digest Hlth & Liver Dis, Miller Sch Med, Miami, FL USA
[7] Vanderbilt Univ Sch Med, Dept Cardiothorac Surg, Nashville, TN USA
[8] Univ Oxford, Nuffield Dept Surg Sci, Oxford, England
[9] LifeShare Transplant Donor Serv Oklahoma, Oklahoma City, OK USA
[10] Baylor Univ Med Ctr, Adm, Dallas, TX USA
[11] Southwest Transplant Alliance, Dallas, TX USA
[12] Washington Univ, Dept Surg Transplantat, St Louis, MO USA
[13] Mayo Clin Arizona, Alix Sch Med, Dept Surg, Div Transplant Surg, Phoenix, AZ USA
[14] Henry Ford Hosp, Div Transplant & Hepatobiliary Surg, Detroit, MI USA
[15] Univ Minnesota, Dept Surg, Minneapolis, MN USA
[16] Hosp Univ La Paz, Gen & Digest Surg, IdiPAZ, Madrid, Spain
关键词
Donation after circulatory death donation (DCD donation); marginal graft; donor pool; machine perfusion (MP); WORKING GROUP-REPORT; LIVER-TRANSPLANTATION; CARDIAC DEATH; MACHINE PERFUSION; ISCHEMIC CHOLANGIOPATHY; FOLLOW-UP; DONORS; DCD; RECOMMENDATIONS; PROCUREMENT;
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Despite a significant increase in utilization over the past decade, the number of donation after circulatory death (DCD) organs that are procured and transplanted in the United States (US) remains well below its potential. There is still room for expansion, as utilizing DCD organs to the fullest extent is currently the most viable solution to the persistent mismatch between supply and demand in transplantation. We convened a multidisciplinary transplantation summit to examine various aspects of DCD, with faculty members from around the world with clinical and academic interest in DCD donation and transplantation, including abdominal and cardiothoracic surgeons, organ procurement organization directors, hepatologists, and gastroenterologists. The conference focused on identifying barriers to DCD organ utilization and strategies to overcome these barriers. We divide the barriers to DCD utilization into three mains categories: (I) policy and process variation; (II) logistical and transportation challenges; and (III) higher risk perceptions related to DCD outcomes. For each barrier, we proposed a variety of solutions, providing an overview of the status of DCD donation in the US and suggestions on how to increase the use of DCD. There is a specific focus on ex situ machine perfusion, normothermic regional perfusion, and other opportunities to expand DCD utilization without negatively impacting recipient outcomes.
引用
收藏
页数:14
相关论文
共 82 条
  • [1] Donation after cardiac death in the US: History and use
    Abt, Peter L.
    Fisher, Carol A.
    Singhal, Arun K.
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2006, 203 (02) : 208 - 225
  • [2] [Anonymous], 1968, J AMER MED ASSOC, V205, P337
  • [3] Liver Transplantation From Controlled Donors After Circulatory Death Using Normothermic Regional Perfusion: An Initial French Experience
    Antoine, Corinne
    Jasseron, Carine
    Dondero, Federica
    Savier, Eric
    [J]. LIVER TRANSPLANTATION, 2020, 26 (11) : 1516 - 1521
  • [4] POLICY STATEMENT Ethical Controversies in Organ Donation After Circulatory Death
    Antommaria, Armand H. Matheny
    Fallat, Mary E.
    Katz, Aviva L.
    Mercurio, Mark R.
    Moon, Margaret R.
    Okun, Alexander L.
    Webb, Sally A.
    Weise, Kathryn L.
    [J]. PEDIATRICS, 2013, 131 (05) : 1021 - 1026
  • [5] Assessment of donor quality and risk of graft failure after liver transplantation: The ID2EAL score
    Asrani, Sumeet K.
    Saracino, Giovanna
    Wall, Anji
    Trotter, James F.
    Testa, Giuliano
    Hernaez, Ruben
    Sharma, Pratima
    Kwong, Allison
    Banerjee, Srikanta
    McKenna, Gregory
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2022, 22 (12) : 2921 - 2930
  • [6] The use of extracorporeal membranous oxygenation in donors after cardiac death
    Barrou, Benoit
    Billault, Claire
    Nicolas-Robin, Armelle
    [J]. CURRENT OPINION IN ORGAN TRANSPLANTATION, 2013, 18 (02) : 148 - 153
  • [7] Trends in Donation After Circulatory Death in Lung Transplantation in the United States: Impact Of Era
    Bobba, Christopher M.
    Whitson, Bryan A.
    Henn, Matthew C.
    Mokadam, Nahush A.
    Keller, Brian C.
    Rosenheck, Justin
    Ganapathi, Asvin M.
    [J]. TRANSPLANT INTERNATIONAL, 2022, 35
  • [8] The economic impact of machine perfusion technology in liver transplantation
    Boteon, Yuri L.
    Hessheimer, Amelia J.
    Bruggenwirth, Isabel M. A.
    Boteon, Amanda P. C. S.
    Padilla, Maria
    de Meijer, Vincent E.
    Dominguez-Gil, Beatriz
    Porte, Robert J.
    Perera, M. Thamara P. R.
    Martins, Paulo N.
    [J]. ARTIFICIAL ORGANS, 2022, 46 (02) : 191 - 200
  • [9] EXPERIENCE WITH LIVER AND KIDNEY ALLOGRAFTS FROM NON-HEART-BEATING DONORS
    CASAVILLA, A
    RAMIREZ, C
    SHAPIRO, R
    NGHIEM, D
    MIRACLE, K
    BRONSTHER, O
    RANDHAWA, P
    BROZNICK, B
    FUNG, JJ
    STARZL, T
    [J]. TRANSPLANTATION, 1995, 59 (02) : 197 - 203
  • [10] Controlled donation after circulatory death up to 80 years for liver transplantation: Pushing the limit again
    Cascales-Campos, Pedro A.
    Ferreras, David
    Alconchel, Felipe
    Febrero, Beatriz
    Royo-Villanova, Mario
    Martinez, Maria
    Rodriguez, Jose M.
    Fernandez-Hernandez, Juan A.
    Rios, Antonio
    Pons, Jose A.
    Sanchez-Bueno, Francisco
    Robles, Ricardo
    Martinez-Barba, Enrique
    Martinez-Alarcon, Laura
    Parrilla, Pascual
    Ramirez, Pablo
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2020, 20 (01) : 204 - 212