Epigallocatechin Gallate (EGCG) Formulations: Unlocking Potential in Nutraceutical and Pharmaceutical Sectors

被引:1
|
作者
Mittal, Ravi K. [1 ]
Mishra, Raghav [2 ,3 ]
Uddin, Rehan [4 ]
Bhargav, Ranjeet [5 ]
Kumar, Neeraj [1 ]
机构
[1] Galgotias Coll Pharm, Greater Noida 201310, Uttar Pradesh, India
[2] Lloyd Sch Pharm, Knowledge Pk 2, Greater Noida 201306, Uttar Pradesh, India
[3] GLA Univ, Dept Pharm, Mathura 281406, Uttar Pradesh, India
[4] Sir Madanlal Inst Pharm, Etawah 206001, Uttar Pradesh, India
[5] Spectrum Inst Pharmaceut Sci & Res, Greater Noida 201310, Uttar Pradesh, India
来源
NATURAL PRODUCTS JOURNAL | 2025年 / 15卷 / 02期
关键词
EGCG formulations; epigallocatechin gallate; polyphenolic compounds; green tea extract; bioavailability; Nutraceuticals; Liposome; lipid nanoparticles; phytosome; MESOPOROUS SILICA NANOPARTICLES; CONTROLLED DRUG-DELIVERY; GREEN TEA POLYPHENOLS; LIPID NANOPARTICLES; (-)-EPIGALLOCATECHIN GALLATE; IN-VITRO; POLYMERIC NANOPARTICLES; ORAL BIOAVAILABILITY; SKIN-CANCER; LIPOSOMES;
D O I
10.2174/0122103155295035240330065048
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Objective This review aims to evaluate the latest techniques used in formulating epigallocatechin gallate (EGCG), analyse the difficulties encountered in the process, and offer perspectives on potential future advancements in epigallocatechin gallate formulations for both nutraceutical and pharmaceutical applications.Methods This work provides a thorough literature review and examines current epigallocatechin gallate formulation strategies, assesses solubility improvement approaches, examines obstacles, and summarises results regarding benefits and drawbacks. In nutraceuticals and pharmaceuticals, it identifies knowledge gaps and suggests future research avenues.Results This comprehensive review presents a synthesis of pivotal discoveries about epigallocatechin gallate formulations, particularly emphasising notable progress in enhancing solubility and the concomitant obstacles encountered in this pursuit. This review weighs the benefits and drawbacks, shedding light on areas that need further investigation in the pharmaceutical and nutraceutical fields.Conclusion This review synthesises current research on formulations containing epigallocatechin gallate, focusing on their various applications and the obstacles accompanying their implementation. Despite facing various challenges, the methodologies that have been investigated demonstrate potential. The comprehensive evaluation of both strengths and limitations highlights the imperative nature of continuous research. The conclusion provides opportunities for research in pharmaceuticals and nutraceuticals, outlining future directions.
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页数:13
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