The Identification and Management of Subthreshold Depression and Anxiety in Primary Care for People With Long-Term Conditions

Background: Subthreshold depression (sDep) and anxiety (sAnx) are common conditions and are associated with significant suffering, impaired functioning, increased healthcare utilisation and economic costs. Furthermore, they are risk factors for crossing the clinical threshold and developing mental health disorders. Subthreshold conditions are associated with long-term conditions (LTCs). This scoping review aimed to explore the identification and management of sDep and sAnx in primary care for patients with LTCs. Methods: We conducted a scoping review, following the Joanna Briggs Institute (JBI) Manual for Evidence Synthesis. Medline, PsycInfo, CINAHL and International Pharmaceutical Abstracts were searched for articles prior to September 2023. We included studies written in English that were conducted among the adult population. All studies that aimed to identify and manage sDep and anxiety in patients with LTC in primary care have been included. Results: Thirty-three articles were included in this scoping review, of which seven studies incorporated an intervention component for sDep and sAnx in patients with LTCs. A variety of definitions and screening tools were used to identify sDep and sAnx. Problem-solving therapy (PST) and behavioural activation (BA) were the most common intervention components and showed promising results. Limitations: We excluded studies that did not explicitly state the terms 'subthreshold', 'subclinical' or 'subsyndromal' depression or anxiety which may be relevant. Conclusion: There is currently limited evidence regarding the identification and management of sDep and sAnx in patients with LTCs, warranting further research.