NRAS tumor mutations are associated with reduced odds of dermatologic adverse events in patients with metastatic melanoma receiving immune checkpoint inhibitors

被引:0
作者
Chang, Michael S. [1 ,2 ]
Said, Jordan T. [1 ,2 ]
Akama-Garren, Elliot H. [1 ,2 ]
Trepanowski, Nicole [2 ,3 ]
Bui, Ai-Tram N. [1 ,2 ]
Giobbie-Hurder, Anita [4 ]
Leboeuf, Nicole R. [1 ,2 ,5 ]
Hartman, Rebecca I. [1 ,2 ,6 ]
机构
[1] Harvard Med Sch, BOSTON, MA USA
[2] Brigham & Womens Hosp, Dept Dermatol, 221 Longwood Ave, Boston, MA 02215 USA
[3] Boston Univ, Sch Med, Boston, MA USA
[4] Dana Farber Canc Inst, Dept Data Sci, Div Biostat, Boston, MA USA
[5] Dana Farber Brigham & Womens Canc Ctr, Ctr Cutaneous Oncol, Boston, MA USA
[6] Vet Integrated Serv Network VISN 1, Dept Dermatol, Jamaica Plain, MA USA
来源
JAAD INTERNATIONAL | 2025年 / 18卷
基金
美国国家卫生研究院;
关键词
anti-PDL-1; atezolizumab; avelumab; cemiplimab; dAE; durvalumab; ICI; ipilimumab; melanoma; mutation; nivolumab; NRAS; pembrolizumab;
D O I
10.1016/j.jdin.2024.11.004
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
[No abstract available]
引用
收藏
页码:165 / 167
页数:3
相关论文
共 50 条
  • [31] Acute neurological adverse events during immune checkpoint inhibition therapy in patients with melanoma brain metastases
    Graetz, Victoria
    Langan, Ewan A.
    Neumann, Alexander
    Zillikens, Detlef
    Terheyden, Patrick
    MELANOMA RESEARCH, 2019, 29 (05) : 516 - 521
  • [32] Efficacy of immune checkpoint inhibitors in patients with anorectal melanoma in association with immune-related adverse events: a case series
    Yokoyama, Reiko
    Sato, Yasushi
    Nakamura, Fumika
    Kagemoto, Kaizo
    Mitsui, Yasuhiro
    Okamoto, Koichi
    Kawano, Yutaka
    Sogabe, Masahiro
    Miyamoto, Hiroshi
    Takayama, Tetsuji
    CLINICAL JOURNAL OF GASTROENTEROLOGY, 2023, 16 (06) : 842 - 847
  • [33] Prognostic role of gamma-glutamyl transferase in metastatic melanoma patients treated with immune checkpoint inhibitors
    Winter, Johanna
    Lenders, Max M.
    Gassenmaier, Maximilian
    Forschner, Andrea
    Leiter, Ulrike
    Weide, Benjamin
    Purde, Mette-Triin
    Flatz, Lukas
    Cozzio, Antonio
    Rocken, Martin
    Garbe, Claus
    Eigentler, Thomas K.
    Wagner, Nikolaus B.
    CANCER IMMUNOLOGY IMMUNOTHERAPY, 2021, 70 (04) : 1089 - 1099
  • [34] Efficacy of immune checkpoint inhibitors in patients with anorectal melanoma in association with immune-related adverse events: a case series
    Reiko Yokoyama
    Yasushi Sato
    Fumika Nakamura
    Kaizo Kagemoto
    Yasuhiro Mitsui
    Koichi Okamoto
    Yutaka Kawano
    Masahiro Sogabe
    Hiroshi Miyamoto
    Tetsuji Takayama
    Clinical Journal of Gastroenterology, 2023, 16 (6) : 842 - 847
  • [35] Plasma Thymidine Kinase Activity as a Novel Biomarker in Metastatic Melanoma Patients Treated with Immune Checkpoint Inhibitors
    Costa Svedman, Fernanda
    Jalsenius, Marie
    Hoeiom, Veronica
    Grozman, Vitali
    Bergqvist, Mattias
    Soederdahl, Fabian
    Eriksson, Hanna
    Rotstein, Samuel
    Ny, Lars
    Ascierto, Paolo A.
    Brage, Suzanne Egyhazi
    Helgadottir, Hildur
    CANCERS, 2022, 14 (03)
  • [36] Efficacy of Immune Checkpoint Inhibitors in Metastatic Melanoma (MM) Patients with Concurrent Chronic Lymphocytic Leukemia (CLL)
    Guerra, Veronica
    Ologun, Gabriel
    Haydu, Lauren
    Keung, Emily
    Burton, Elizabeth
    Tawbi, Hussein
    Davis, Michael
    Wargo, Jennifer
    Ferrajoli, Alessandra
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2020, 20 : S225 - S225
  • [37] Cardiovascular Immunotoxicity Associated with Immune Checkpoint Inhibitors in Metastatic Melanoma
    L'Orphelin, Jean-Matthieu
    Dollalille, Charles
    Akroun, Julia
    Alexandre, Joachim
    Dompmartin, Anne
    CANCERS, 2023, 15 (07)
  • [38] New Zealand national retrospective cohort study of survival outcomes of patients with metastatic melanoma receiving immune-checkpoint inhibitors
    Ab Rahman, Ahmad Sufian
    Strother, Robert Matthew
    Paddison, Johanna
    ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 2023, 19 (01) : 179 - 186
  • [39] Timeline of Adverse Events during Immune Checkpoint Inhibitors for Advanced Melanoma and Their Impacts on Survival
    Villa-Crespo, Lorena
    Podlipnik, Sebastian
    Anglada, Natalia
    Izquierdo, Clara
    Giavedoni, Priscila
    Iglesias, Pablo
    Dominguez, Mireia
    Aya, Francisco
    Arance, Ana
    Malvehy, Josep
    Puig, Susana
    Carrera, Cristina
    CANCERS, 2022, 14 (05)
  • [40] Effect of Cancer Stage on Adverse Kidney Outcomes in Patients Receiving Immune Checkpoint Inhibitors for Melanoma
    Wang, Qiyu
    Strohbehn, Ian A.
    Zhao, Sophia
    Seethapathy, Harish
    Strohbehn, Samuel D.
    Hanna, Paul
    Lee, Meghan
    Fadden, Riley
    Sullivan, Ryan J.
    Boland, Genevieve M.
    Reynolds, Kerry L.
    Sise, Meghan E.
    KIDNEY INTERNATIONAL REPORTS, 2022, 7 (11): : 2517 - 2521