Management Options for Node-Positive Muscle-Invasive Bladder Cancer

被引：0

作者：

Polimera, V. ^{[1
]}

Bhatia, Priyanka ^{[1
]}

Wheelden, Megan ^{[1
]}

Perimbeti, Stuthi ^{[1
]}

Warrick, Joshua ^{[2
]}

Joshi, Monika ^{[1
]}

机构：

[1] Penn State Canc Inst, Dept Med, Div Hematol Oncol, Hershey, PA USA

[2] Penn State Hershey Med Ctr, Dept Pathol, Hershey, PA USA

来源：

CLINICAL ADVANCES IN HEMATOLOGY & ONCOLOGY | 2024年 / 22卷 / 08期

关键词：

Biomarker; chemotherapy; immunotherapy; node-positive muscle-invasive bladder cancer; radiation; METASTATIC UROTHELIAL CARCINOMA; CISPLATIN-INELIGIBLE PATIENTS; ADJUVANT CHEMOTHERAPY; OPEN-LABEL; NEOADJUVANT CHEMOTHERAPY; RADICAL CYSTECTOMY; SINGLE-ARM; TRANSURETHRAL SURGERY; MULTICENTER; THERAPY;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Localized node-positive bladder cancer is characterized by a high degree of heterogeneity, leading to significant variability in overall survival outcomes among affected individuals. The absence of standardized treatment guidelines presents a critical challenge in managing these patients effectively. This comprehensive review article delves into the pathophysiology, clinical significance, and management of node-positive bladder cancer. It critically evaluates the current therapeutic landscape and explores emerging treatment strategies, including novel drugs currently undergoing clinical trials. By synthesizing the latest research findings, the review aims to provide valuable insights into the optimal management of node-positive urothelial cell carcinoma, ultimately contributing to improved patient outcomes and quality of life.

引用

页码：392 / 402

页数：11

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