Synthesis of Trifluoromethylselenolated Spiro[5.5]trienones/Spiro[4.5]trienones via Electrophilic Trifluoromethylselenolation Cyclization and Dearomatization

被引：0
|
作者：
Wang, Jia [1 ]
Niu, Jia-Qi [1 ]
Geng, Ming-Jiang [1 ]
Li, Jia-Cheng [1 ]
Yan, Yun-Hui [1 ]
Liu, Lixia [1 ]
Shang, Xuefang [1 ]
Chao, Shu-Jun [1 ]
机构：
[1] Xinxiang Med Univ, Xinxiang Engn Technol Res Ctr Funct Med Nanomat, Sch Basic Med Sci, Xinxiang 453003, Henan, Peoples R China
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2024年
关键词：
Trifluoromethylselenolated spiro[5.5]trienones; Trifluoromethylselenolated spiro[4.5]trienones; <italic>N</italic>-trifluoromethylselenophthalimide; Trifluoromethylselenolation cyclization; CONSTRUCTION; REAGENT;
D O I：
10.1002/adsc.202401099
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
An expedient strategy for the construction of trifluoromethylselenolated spiro[5.5]trienones/spiro[4.5]trienones through a cascade electrophilic trifluoromethylselenolation cyclization and dearomatization has been developed. This sequential process was induced by N-trifluoromethylselenophthalimide (Phth-SeCF3), which was an efficient electrophilic trifluoromethylselenolation reagent. This approach has the feature of mild conditions, broad substrate scope, and high functional group tolerance.
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页数：7
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