Synthesis of Trifluoromethylselenolated Spiro[5.5]trienones/Spiro[4.5]trienones via Electrophilic Trifluoromethylselenolation Cyclization and Dearomatization

被引：0

作者：

Wang, Jia ^{[1
]}

Niu, Jia-Qi ^{[1
]}

Geng, Ming-Jiang ^{[1
]}

Li, Jia-Cheng ^{[1
]}

Yan, Yun-Hui ^{[1
]}

Liu, Lixia ^{[1
]}

Shang, Xuefang ^{[1
]}

Chao, Shu-Jun ^{[1
]}

机构：

[1] Xinxiang Med Univ, Xinxiang Engn Technol Res Ctr Funct Med Nanomat, Sch Basic Med Sci, Xinxiang 453003, Henan, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2024年

关键词：

Trifluoromethylselenolated spiro[5.5]trienones; Trifluoromethylselenolated spiro[4.5]trienones; <italic>N</italic>-trifluoromethylselenophthalimide; Trifluoromethylselenolation cyclization; CONSTRUCTION; REAGENT;

D O I：

10.1002/adsc.202401099

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

An expedient strategy for the construction of trifluoromethylselenolated spiro[5.5]trienones/spiro[4.5]trienones through a cascade electrophilic trifluoromethylselenolation cyclization and dearomatization has been developed. This sequential process was induced by N-trifluoromethylselenophthalimide (Phth-SeCF3), which was an efficient electrophilic trifluoromethylselenolation reagent. This approach has the feature of mild conditions, broad substrate scope, and high functional group tolerance.

引用

页数：7

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