DXA-derived abdominal fat-free mass to predict MRI skeletal muscle mass in postmenopausal women

被引:0
|
作者
Walker, E. [1 ]
Chalke, A. M. [1 ]
Bland, V. L. [2 ]
Lind, K. E. [3 ]
Chen, Z. [1 ]
Blew, R. M. [3 ]
Odegaard, A. O. [4 ]
Thomson, C. A. [3 ]
Caan, B. [5 ]
Nicholas, J. S. [6 ]
Valencia, C. I. [7 ]
Roe, D. J. [1 ]
Allison, M. [8 ]
Schnatz, P. F. [9 ]
Wactawski-Wende, J. [10 ]
Bea, J. W. [3 ]
机构
[1] Univ Arizona, Mel & Enid Zuckerman Coll Publ Hlth, Dept Epidemiol & Biostat, Tucson, AZ USA
[2] Univ Arizona, Sch Nutr Sci & Wellness, Tucson, AZ USA
[3] Univ Arizona, Mel & Enid Zuckerman Coll Publ Hlth, Dept Hlth Promot Sci, Tucson, AZ 85721 USA
[4] Univ Calif Irvine, Dept Epidemiol & Biostat, Irvine, CA USA
[5] Kaiser Permanente Div Res, Oakland, CA USA
[6] Univ Arizona, Coll Pharm, Tucson, AZ USA
[7] Univ Arizona, Coll Med Tucson, Dept Family & Community Med, Tucson, AZ USA
[8] Univ Calif San Diego, Family Med & Publ Hlth, San Diego, CA USA
[9] Drexel Univ, Coll Med, Dept Obstet & Gynecol, Philadelphia, PA USA
[10] SUNY Buffalo, Sch Publ Hlth & Hlth Profess, Buffalo, NY USA
基金
美国国家卫生研究院;
关键词
postmenopause; body composition; absorptiometry; abdominal muscle mass; magnetic resonance imaging; lean mass; X-RAY ABSORPTIOMETRY; ADIPOSE-TISSUE; CANCER;
D O I
暂无
中图分类号
S3 [农学(农艺学)];
学科分类号
0901 ;
摘要
Dual-energy X-ray absorptiometry (DXA) is more available than gold-standard magnetic resonance imaging (MRI), but DXA ability to estimate abdominal skeletal muscle mass (SMM) is unknown. DXA-derived abdominal fat-free mass (FFM; Hologic QDR2000 or QDR4500w) was correlated with single-slice MRI SMM at L4 (N = 69; r QDR2000 = 0.71, QDR4500w = 0.69; p < 0.0001). Linear regression to predict SMM, including DXA FFM, BMI, and age, resulted in an R-squared of 0.72 and 0.65 for QDR2000 and QDR4500. Bland-Altman limits of agreement were +/- 21 and +/- 31 g for 2-3 standard deviations from the mean difference. DXA predicted abdominal SSM is a moderate proxy for MRI abdominal SMM.
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页数:5
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