Iodine-mediated regioselective C-3 sulfenylation using elemental sulfur and arylhydrazine hydrochloride to access 3-sulfenylated imidazo[1,2-a]pyridines

被引：0

作者：

Kishor, Kaushal ^{[1
]}

Prabhakar, Neha Sharma ^{[1
]}

Singh, Krishna Nand ^{[1
]}

机构：

[1] Banaras Hindu Univ, Inst Sci, Dept Chem, Varanasi 221005, India

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2025年 / 23卷 / 10期

关键词：

PYRIDINE-DERIVATIVES; IMIDAZOPYRIDINES; ACIDS;

D O I：

10.1039/d4ob02095b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A transition metal-free protocol for the regioselective C-3 sulfenylation of imidazo[1,2-a]pyridines has been explored using arylhydrazine hydrochloride and elemental sulfur, in the presence of molecular iodine and DABCO via C(sp2)-H functionalization to achieve structurally diverse 3-sulfenylated imidazo[1,2-a]pyridines in reasonably high yields.

引用

页码：2418 / 2423

页数：6

共 22 条

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[22] I2O5-Mediated Iodocyclization Cascade of N-(1-Arylallyl)pyridine-2-amines with Concomitant C=C Bond Cleavage: A Synthesis of 3-Iodoimidazo[1,2-a]pyridines
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