Chromium catalyzed acceptorless dehydrogenative (cross)coupling of primary amines to secondary imines

被引：0

作者：

Anand, Aman ^{[1
]}

Regina, Anitta ^{[1
]}

Jalwal, Sachin ^{[1
]}

Prodhan, Soumojyati ^{[2
]}

Sil, Debangsu ^{[2
]}

Paranjothy, Manikandan ^{[1
]}

Chakraborty, Subrata ^{[1
]}

机构：

[1] Indian Inst Technol Jodhpur, Dept Chem, Jodhpur 342030, Rajasthan, India

[2] Indian Inst Sci Educ & Res Pune, Dept Chem, Dr Homi Bhabha Rd, Pashan, Pune 411008, India

来源：

DALTON TRANSACTIONS | 2025年 / 54卷 / 16期

关键词：

BORROWING HYDROGEN; OXIDATIVE ADDITION; AEROBIC OXIDATION; HYDROAMINATION; COMPLEXES; NITRILES; ALCOHOLS; METALS; FORM;

D O I：

10.1039/d4dt03460k

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

We present here acceptorless dehydrogenative coupling of primary amines to form secondary aldimines catalyzed by a complex of Earth-abundant chromium. The reaction is promoted by Cr(DAFO)(CO)4 (DAFO = 4,5-diazafluorene-9-one) without using any additives, base or oxidant generating NH3 and H2 as sole by-products. Dehydrogenative cross-coupling of primary amines with aniline derivatives to unsymmetrical secondary imines was also achieved with good to excellent yields. A probable mechanism is proposed based on the stoichiometric investigation and computational studies.

引用

页码：6432 / 6442

页数：11

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