Harnessing nature's arsenal: A comprehensive review of phytomedicine approaches in Monkeypox treatment

The recent global outbreak of monkeypox has highlighted the urgent need for effective treatments against this emerging viral threat. Despite the limitations of conventional antiviral therapies, phytomedicine presents a promising avenue for further exploration. This review examines the potential of plant-derived compounds in addressing monkeypox, focusing on recent advancements in phytochemical research and traditional medicine approaches. We analysed key phytochemicals, including curcumin derivatives, flavonoids, triterpenes, and alkaloids, discussing their mechanisms of action and potential efficacy against the monkeypox virus. The review also explores insights from traditional Chinese medicine and other traditional healing systems. Challenges in phytomedicine development, including bioavailability issues and standardisation, are addressed, along with future research directions. This comprehensive analysis provides a foundation for harnessing nature's arsenal in the fight against monkeypox, offering insights into potential phytomedicine-based strategies for prevention and treatment.