Copper-Catalyzed 1,5-Trifluoromethyl-thio(seleno)cyanation of 5-Hexenenitriles with an Intramolecular Cyano Migration

被引：0
作者：
Sun, Yining [1 ]
Wang, Zhixian [1 ]
Wang, Jiaqi [1 ]
Guo, Kang [1 ]
机构：
[1] Hebei Normal Univ Nationalities, Chengde, Hebei, Peoples R China
来源：
CHEMISTRY-AN ASIAN JOURNAL | 2025年
关键词：
thiocyanation; selenocyanation; cyano migration; trifluoromethylation; copper catalysis; THIOCYANATES; CHEMISTRY; FLUORINE; ALKENES;
D O I：
10.1002/asia.202500241
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A copper-catalyzed remote 1,5-trifluoromethyl thio(seleno)cyanation of 5-hexenenitriles with an intramolecular cyano migration has been established, affording a variety of CF3/CN-containing thiocyanates and selenocyanates under mild conditions. The reaction features high chemo- and regioselectivities and illustrates potential value in synthetic chemistry.
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页数：5
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