Pneumonia: Recent Updates on Diagnosis and Treatment

被引:0
作者
Khan, Maaz Ahsan [1 ]
Bajwa, Awais [2 ]
Hussain, Syed Talal [2 ]
机构
[1] Univ Oklahoma, Dept Internal Med, Oklahoma City, OK 73104 USA
[2] Univ Oklahoma, Dept Pulm Crit Care & Sleep Med, Oklahoma City, OK 73104 USA
关键词
pneumonia; syndromic panels; antibiotic stewardship; new treatments; respiratory panel; VENTILATOR-ASSOCIATED PNEUMONIA; COMMUNITY-ACQUIRED PNEUMONIA; MULTICENTER; INHALATION; ARBEKACIN; AMIKACIN; DISEASES; SYSTEM;
D O I
10.3390/microorganisms13030522
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Pneumonia remains a leading cause of mortality internationally, making it an intense area of study for new tools for diagnosis and treatment. In this review, we evaluate the potential of recently emerging syndromic panels in promoting rapid diagnosis and improved antibiotic stewardship. We will also examine emerging treatments, including new antibiotics in a world of worsening antimicrobial resistance, in addition to new methods of delivery and non-antibiotic paths of treatment.
引用
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页数:12
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共 63 条
[1]   Multiplex real-time PCR in non-invasive respiratory samples to reduce antibiotic use in community-acquired pneumonia: a randomised trial [J].
Abelenda-Alonso, Gabriela ;
Calatayud, Laura ;
Rombauts, Alexander ;
Meije, Yolanda ;
Oriol, Isabel ;
Sopena, Nieves ;
Padulles, Ariadna ;
Niubo, Jordi ;
Duarte, Alejandra ;
Llaberia, Jaume ;
Aranda, Judit ;
Gudiol, Carlota ;
Satorra, Pau ;
Tebe, Cristian ;
Ardanuy, Carmen ;
Carratala, Jordi .
NATURE COMMUNICATIONS, 2024, 15 (01)
[2]   It's about the patients: Practical antibiotic stewardship in outpatient settings in the United States [J].
Amin, Alpesh N. ;
Dellinger, E. Patchen ;
Harnett, Glenn ;
Kraft, Bryan D. ;
LaPlante, Kerry L. ;
LoVecchio, Frank ;
McKinnell, James A. ;
Tillotson, Glenn ;
Valentine, Salisia .
FRONTIERS IN MEDICINE, 2022, 9
[3]   Specialized pro-resolving mediators: endogenous regulators of infection and inflammation [J].
Basil, Maria C. ;
Levy, Bruce D. .
NATURE REVIEWS IMMUNOLOGY, 2016, 16 (01) :51-67
[4]   New Antibiotics for Hospital-Acquired Pneumonia and Ventilator-Associated Pneumonia [J].
Bassetti, Matteo ;
Mularoni, Alessandra ;
Giacobbe, Daniele Roberto ;
Castaldo, Nadia ;
Vena, Antonio .
SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE, 2022, 43 (02) :280-294
[5]   Trimannose-coupled antimiR-21 for macrophage-targeted inhalation treatment of acute inflammatory lung damage [J].
Beck, Christina ;
Ramanujam, Deepak ;
Vaccarello, Paula ;
Widenmeyer, Florenc ;
Feuerherd, Martin ;
Cheng, Cho-Chin ;
Bomhard, Anton ;
Abikeeva, Tatiana ;
Schaedler, Julia ;
Sperhake, Jan-Peter ;
Graw, Matthias ;
Safi, Seyer ;
Hoffmann, Hans ;
Staab-Weijnitz, Claudia A. A. ;
Rad, Roland ;
Protzer, Ulrike ;
Frischmuth, Thomas ;
Engelhardt, Stefan .
NATURE COMMUNICATIONS, 2023, 14 (01)
[6]  
BioFire, BIOFIRE® FILMARRAY® Pneumonia (PN) Panels
[7]   Practical Comparison of the BioFire FilmArray Pneumonia Panel to Routine Diagnostic Methods and Potential Impact on Antimicrobial Stewardship in Adult Hospitalized Patients with Lower Respiratory Tract Infections [J].
Buchan, Blake W. ;
Windham, Sam ;
Balada-Llasat, Joan-Miquel ;
Leber, Amy ;
Harrington, Amanda ;
Relich, Ryan ;
Murphy, Caitlin ;
Bard, Jennifer Dien ;
Naccache, Samia ;
Ronen, Shira ;
Hopp, Amanda ;
Mahmutoglu, Derya ;
Faron, Matthew L. ;
Ledeboer, Nathan A. ;
Carroll, Amanda ;
Stone, Hannah ;
Akerele, Oluseun ;
Everhart, Kathy ;
Bonwit, Andrew ;
Kwong, Christina ;
Buckner, Rebecca ;
Del Warren ;
Fowler, Randal ;
Chandrasekaran, Sukantha ;
Huse, Holly ;
Campeau, Shelley ;
Humphries, Romney ;
Graue, Corrin ;
Huang, Angela .
JOURNAL OF CLINICAL MICROBIOLOGY, 2020, 58 (07)
[8]   Ten Issues for Updating in Community-Acquired Pneumonia: An Expert Review [J].
Candel, Francisco Javier ;
Salavert, Miguel ;
Basaras, Miren ;
Borges, Marcio ;
Canton, Rafael ;
Cercenado, Emilia ;
Cilloniz, Catian ;
Estella, Angel ;
Garcia-Lechuz, Juan M. ;
Garnacho Montero, Jose ;
Gordo, Federico ;
Julian-Jimenez, Agustin ;
Martin-Sanchez, Francisco Javier ;
Maseda, Emilio ;
Matesanz, Mayra ;
Menendez, Rosario ;
Miron-Rubio, Manuel ;
de Lejarazu, Raul Ortiz ;
Polverino, Eva ;
Retamar-Gentil, Pilar ;
Ruiz-Iturriaga, Luis Alberto ;
Sancho, Susana ;
Serrano, Leyre .
JOURNAL OF CLINICAL MEDICINE, 2023, 12 (21)
[9]   Evaluation of point-of-care multiplex polymerase chain reaction in guiding antibiotic treatment of patients acutely admitted with suspected community-acquired pneumonia in Denmark: A multicentre randomised controlled trial [J].
Cartuliares, Mariana Bichuette ;
Rosenvinge, Flemming Schonning ;
Mogensen, Christian Backer ;
Skovsted, Thor Aage ;
Andersen, Steen Lomborg ;
Ostergaard, Claus ;
Pedersen, Andreas Kristian ;
Skjot-arkil, Helene .
PLOS MEDICINE, 2023, 20 (11)
[10]   Lefamulin: The First Systemic Pleuromutilin Antibiotic [J].
Chahine, Elias B. ;
Sucher, Allana J. .
ANNALS OF PHARMACOTHERAPY, 2020, 54 (12) :1203-1214