Prediction of Health Status in Patients Undergoing Lower Extremity Intervention for Claudication

被引:0
作者
Peri-Okonny, Poghni A. [1 ]
Romain, Gaelle [1 ]
Callegari, Santiago [1 ]
Cleman, Jacob [1 ]
Vashist, Aseem [1 ]
Smolderen, Kim G. [1 ]
Mena-Hurtado, Carlos [1 ,2 ]
机构
[1] Yale Univ, Dept Internal Med, Sect Cardiol, Vasc Med Outcomes Program, New Haven, CT USA
[2] Yale Univ, Dept Psychiat, New Haven, CT USA
关键词
PERIPHERAL ARTERIAL-DISEASE; DRUG-COATED BALLOON; WALKING IMPAIRMENT; RISK-FACTORS; QUESTIONNAIRE; MORTALITY; PREVALENCE; EUROQOL;
D O I
10.1016/j.avsg.2024.08.016
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background: Identifying predictors of generic and disease-specific health status outcomes in patients with lower extremity peripheral artery disease who undergo femoral-popliteal peripheral vascular intervention (PVI) for claudication remains an understudied area. We aimed to identify important predictors of health status after PVI as the foundation for risk-based approaches to deploying therapies that improve patient outcomes. Method: Baseline characteristics of 468 participants with claudication and femoral/popliteal stenosis treated with either the Stellarex paclitaxel-based drug-coated balloon or plain balloon angioplasty from 2013 to 2019 were included. The study examined 59 baseline variables and aimed to identify the most important predictors of generic (EQ-5D-3L and EQ-5D visual analog scale [VAS]) and disease-specific (Walking Impairment Questionnaire [WIQ]) health status at 1 year. A random forest model was used to generate a rank variables based on their importance in predicting 1-year health status. Results: Among included patients, mean +/- standard deviation age was 68.3 +/- 9 years with 67.9% and 87% being male and White, respectively. Baseline mean EQ-5D-3L, EQ-5D VAS, and WIQ were 0.7 +/- 0.3, 64.6 +/- 16.0, and 30.7 +/- 22.1, respectively. The most important variables for predicting EQ-5D-3L, EQ-5D VAS, and WIQ were a history of deep venous thrombosis, chronic lung disease, and hypertension, respectively. Conclusions: Among patients undergoing PVI for claudication, comorbidities were the most important predictors of future health status, underscoring the need for an integrated approach for peripheral artery disease management. Utilization of machine learning approaches can facilitate development of models to inform risk-based approaches to treatment.
引用
收藏
页码:314 / 322
页数:9
相关论文
共 50 条
  • [31] Ten-year clinical outcomes for patients undergoing lower extremity endovascular interventions
    Katsuki, Tomonori
    Yamaji, Kyohei
    Hiramori, Seiichi
    Tomoi, Yusuke
    Soga, Yoshimitsu
    Ando, Kenji
    JOURNAL OF VASCULAR SURGERY, 2020, 72 (05) : 1626 - +
  • [32] How Much Are Upper or Lower Extremity Disabilities Associated with General Health Status in the Elderly?
    Roh, Young Hak
    Kim, Ki Woong
    Paik, Nam-Jong
    Kim, Tae Kyun
    Gong, Hyun Sik
    CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 2012, 470 (11) : 3246 - 3252
  • [33] Knowledge and attitude of patients undergoing lower extremity amputation at RK Khan Hospital, Chatsworth
    Olotu, B.
    Anderson, F.
    SOUTH AFRICAN JOURNAL OF SURGERY, 2019, 57 (04) : 9 - 13
  • [34] Factors associated with lower-extremity amputation in patients with diabetic foot ulcers in a Chinese tertiary care hospital
    Guo, Zi
    Yue, Chun
    Qian, Qiang
    He, Honghui
    Mo, Zhaohui
    INTERNATIONAL WOUND JOURNAL, 2019, 16 (06) : 1304 - 1313
  • [35] Current status of lower-extremity revascularization
    Friedell, Mark L.
    Stark, Karl R.
    Kujath, Scott W.
    Carter, Robert R.
    CURRENT PROBLEMS IN SURGERY, 2014, 51 (06) : 254 - 290
  • [36] Prediction of Coronary Artery Disease in Patients With Lower Extremity Peripheral Artery Disease
    Cho, Sung Woo
    Kim, Byung Gyu
    Kim, Deok Hee
    Kim, Byung Ok
    Byun, Young Sup
    Rhee, Kun Joo
    Lee, Byoung Kwon
    Goh, Choong Won
    INTERNATIONAL HEART JOURNAL, 2015, 56 (02) : 209 - 212
  • [37] Impact of the community's socioeconomic status on characteristics and outcomes of patients undergoing percutaneous coronary intervention
    Shimony, Avi
    Zahger, Doron
    Ilia, Reuben
    Shalev, Aryeh
    Cafri, Carlos
    INTERNATIONAL JOURNAL OF CARDIOLOGY, 2010, 144 (03) : 379 - 382
  • [38] Pre-operative predictors of poor outcomes in patients undergoing surgical lower extremity revascularisation - Retrospective cohort study
    Ashrafi, Mohammed
    Salvadi, Rohini
    Foden, Philip
    Thomas, Stephanie
    Baguneid, Mohamed
    INTERNATIONAL JOURNAL OF SURGERY, 2017, 41 : 91 - 96
  • [39] Effect of in-hospital physical activity on cardiovascular prognosis in lower extremity bypass for claudication
    Matsuo, Tomohiro
    Sakaguchi, Taichi
    Ishida, Atsuhisa
    Yuguchi, Satoshi
    Saito, Kazuya
    Nakajima, Masaharu
    Ujikawa, Takuya
    Morisawa, Tomoyuki
    Chikazawa, Genta
    Takahashi, Tetsuya
    JOURNAL OF PHYSICAL THERAPY SCIENCE, 2015, 27 (06) : 1855 - 1859
  • [40] Prognostic Value of Radiotracer-Based Perfusion Imaging in Critical Limb Ischemia Patients Undergoing Lower Extremity Revascularization
    Chou, Ting-Heng
    Alvelo, Jessica L.
    Janse, Sarah
    Papademetris, Xenophon
    Sumpio, Bauer E.
    Mena-Hurtado, Carlos
    Sinusas, Albert J.
    Stacy, Mitchel R.
    JACC-CARDIOVASCULAR IMAGING, 2021, 14 (08) : 1614 - 1624