Alpha-Fetoprotein-Producing Hepatoid Adenocarcinoma of the Stomach

被引：0

作者：

Bathobakae, Lefika ^{[1
]}

Elagami, Mohamed ^{[2
]}

Mahmoud, Anas ^{[1
]}

Kesrani, Jaydev ^{[3
]}

Yuridullah, Ruhin ^{[2
]}

Melki, Gabriel ^{[2
]}

Akmal, Amer ^{[4
]}

Cavanagh, Yana ^{[2
]}

Baddoura, Walid ^{[2
]}

机构：

[1] St Josephs Univ, Med Ctr, Internal Med, Paterson, NJ 07503 USA

[2] St Josephs Univ, Med Ctr, Gastroenterol & Hepatol, Paterson, NJ USA

[3] St Josephs Univ, Med Ctr, Hematol & Oncol, Paterson, NJ USA

[4] St Josephs Univ, Med Ctr, Pathol & Lab Med, Paterson, NJ USA

来源：

JOURNAL OF MEDICAL CASES | 2024年 / 15卷 / 10期

关键词：

Alpha-fetoprotein-producing gastric cancer; Hepatoid adenocarcinoma of the stomach; Abdominal pain; Palliative chemo- therapy; GASTRIC-CANCER;

D O I：

10.14740/jmc4263

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hepatoid adenocarcinoma of the stomach (HAS) is a rare type of gastric cancer with unique clinicopathological features. HAS has a poor prognosis because of early liver, lung, and lymph node metastasis. Owing to its rarity and malignant potential, data on its pathophysiology and management are scarce. Herein, we describe a case of alpha-fetoprotein-producing HAS (AFP-HAS) with metastases to the liver, lungs, and spine. The patient presented with a 3-month history of epigastric pain and intractable emesis, initially thought to be gastroparesis given her uncontrolled diabetes mellitus. Contrast-enhanced computerized tomography (CECT) of the abdomen and pelvis revealed thickening of the gastric wall with hepatic metastases. Upper endoscopy revealed a fungating gastric mass, and the histopathology confirmed AFP-HAS. The patient did not tolerate palliative chemotherapy and died 6 months after her gastric cancer diagnosis.

引用

页码：304 / 309

页数：6

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