Retention in care among people living with human immunodeficiency virus (HIV) in a low-resource setting

被引：0

作者：

Cordie, Ahmed ^{[1
,2
]}

Mohamed, Rahma ^{[1
,2
]}

Hatem, Ammar ^{[1
]}

Essam, Mahmoud ^{[1
]}

Shaltout, Shaker Wagih ^{[3
]}

El Garhy, Naeema ^{[1
]}

Al Sehemy, Lamiaa ^{[1
]}

Sherif, Mirella ^{[1
]}

Awad, Reham Awad ^{[1
]}

Abdelraouf, Mariam Ismail ^{[1
]}

Al-sharif, Aya M. ^{[1
]}

Ramadan, Ahmed ^{[4
]}

Hassany, Sahar ^{[5
]}

El Khateeb, Engy ^{[6
]}

Sayed, Amal M. ^{[6
]}

Masoud, Zainab Wafik Zakaria ^{[6
]}

Hamza, Rania Soliman ^{[6
]}

Tamim, Hend Hamed ^{[6
]}

Hamdy, Mona Salah Eldin ^{[6
]}

Esmat, Gamal ^{[1
,7
]}

Ramadan, Haidi Karam-Allah ^{[5
]}

机构：

[1] Cairo Univ, Endem Med Dept, Al-Saray St El Manial, Cairo 11956, Egypt

[2] Cairo Univ, Cairo Univ Hosp, Kasr Al Aini HIV & Viral Hepatitis Fighting Grp, Cairo, Egypt

[3] Port Said Univ, Trop Med Dept, Port Said, Egypt

[4] Univ Sherbrooke, Fac Engn, Dept Chem & Biotechnol Engn, Sherbrooke, PQ, Canada

[5] Assiut Univ, Dept Trop Med & Gastroenterol, Assiut, Egypt

[6] Cairo Univ, Dept Clin & Chem Pathol, Cairo, Egypt

[7] Badr Univ Cairo, Res Ctr, Cairo, Egypt

来源：

INTERNATIONAL JOURNAL OF STD & AIDS | 2025年 / 36卷 / 04期

关键词：

Retention in care; human immunodeficiency virus; viral load; mortality; low-resource setting; ANTIRETROVIRAL THERAPY; ADULT PATIENTS;

D O I：

10.1177/09564624241306152

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Background This study aimed to evaluate the retention in care among a cohort of Egyptian people living with HIV (PLWHIV).Method The study was conducted on PLWHIV attending Kasr Alainy HIV and Viral Hepatitis Centre, Cairo, Egypt, from January 1, 2019, to March 31, 2023. PLWHIV were considered not retained in care if there was no documented clinical visit or HIV viral load (VL) or CD4 count test for more than 6 months from their last recorded visit or test. Multivariable logistic regression analysis was used to test factors associated with retention in care.Results After excluding those who died and were referred, 369 PLWHIV were included in the analysis, and retention in care was observed in 325 (88%). The majority were males (81.8%) with a median age of 34 [29-41] years. Undetectable VL (OR: 3.555; 95% CI: 1.49-8.47), hepatitis B vaccination (OR: 2.835; 95% CI: 1.07-7.48), CD4 test availability (OR: 2.604; 95% CI: 1.02-6.64), receiving dolutegravir based antiretroviral therapy (OR: 2.429; 95% CI: 1.06-5.537), and longer duration of know HIV infection (OR: 1.025; 95% CI: 1.01- 1.04) were correlated with retention in care. Surprisingly, higher education levels were negatively correlated with retention in care (OR: 0.195, 95%: CI: 0.071-0.533), suggesting the need for further research to explore this relationship.Conclusion These results are invaluable for developing targeted interventions and informing health policies to improve retention in HIV care in Egypt. Enhancing access to VL and CD4 testing, promoting VL suppression, and focusing on specific groups at risk of dropping out of care are essential strategies.

引用

页码：275 / 282

页数：8

共 28 条

[1]

[Anonymous], 2016, Global AIDS update 2016

[2]

[Anonymous], 2015, Yemen: Childhood Under Threat

[3]

Antinori A, 2017, NEW MICROBIOL, V40, P86

[4] Predictors of loss to follow-up among patients on ART at a rural hospital in KwaZulu-Natal, South Africa [J].