Epstein-Barr virus-associated B-cell lymphoproliferative disorders and lymphomas: Diagnostic overlaps and defining features

被引：1

作者：

Volaric, Ashley K. ^{[1
]}

Fedoriw, Yuri ^{[2
]}

机构：

[1] Univ Vermont, Dept Pathol & Lab Med, Larner Coll Med, 89 Beaumont Ave, Burlington, VT 05405 USA

[2] Univ North Carolina, Lineberger Comprehens Canc Ctr, Dept Pathol & Lab Med, Sch Med, 160 Med Dr,Brinkhouse Bullitt Bldg,CB 7525, Chapel Hill, NC 27599 USA

来源：

HUMAN PATHOLOGY | 2025年 / 156卷

关键词：

Epstein-Barr virus; EBV; B -Cell lymphoproliferative disorder; B -Cell lymphoma; Immunodeficiency; Post-transplant; Mucocutaneous ulcer; Classic Hodgkin lymphoma; Diffuse large B -Cell lymphoma; Polymorphic B -Cell lymphoproliferative; disorder; POSITIVE MUCOCUTANEOUS ULCER; IN-SITU HYBRIDIZATION; HODGKIN LYMPHOMA; FRENCH REGISTRY; EBV; DISEASE; INFECTION; DNA;

D O I：

10.1016/j.humpath.2024.105697

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

This review explores four Epstein-Barr virus (EBV)-associated B-cell lymphoproliferative disorders (LPD) and lymphomas with significant diagnostic overlap: EBV(+) mucocutaneous ulcer (EBVMCU), EBV(+) polymorphic LPD, EBV(+) classic Hodgkin lymphoma (CHL), and EBV(+) diffuse large B-cell lymphoma (DLBCL). Each entity is compared for both overlapping and defining features of clinical presentation, morphology, immunohistochemical profile and EBV expression pattern and latency. Our aims for this review are to provide useful guidance to the practicing pathologist in the diagnosis of these EBV-associated entities.

引用

页数：9

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