Enhanced magnetic hyperthermia performance in thermal plasma synthesized MnFe2O4 nanoparticles

被引：0

作者：

Deka, Kashmiri ^{[1
]}

Deshpande, Gauri A. ^{[1
]}

Kamble, Shalaka A. ^{[1
]}

Varma, Vijaykumar B. ^{[2
]}

Ramanujan, R. V. ^{[3
]}

Khot, Priyanka ^{[4
]}

Kodam, Kisan M. ^{[4
]}

Kaushik, Som Datta ^{[5
]}

Babu, P. D. ^{[5
]}

Mathe, Vikas L. ^{[1
]}

机构：

[1] Savitribai Phule Pune Univ, Dept Phys, Plasma Nanomat Lab, Pune 411007, Maharashtra, India

[2] Luxembourg Inst Sci & Technol, 41 Rue Brill, L-4422 Belvaux, Luxembourg

[3] Nanyang Technol Univ, Sch Mat Sci & Engn, Singapore 639798, Singapore

[4] Savitribai Phule Pune Univ, Dept Chem, Pune 411007, Maharashtra, India

[5] BARC, DAE Consortium Sci Res, Mumbai Ctr, UGC, Mumbai 400085, India

来源：

JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS | 2025年 / 200卷

关键词：

Magnetic hyperthermia; Thermal plasma; Magnetic nanomaterials; Manganese ferrite; IRON-OXIDE NANOPARTICLES; ELECTRICAL-PROPERTIES; IN-VITRO; TEMPERATURE; DELIVERY; REMOVAL; SYSTEM; VIVO;

D O I：

10.1016/j.jpcs.2025.112586

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Spherical manganese ferrite (MnFe2O4) nanoparticles (MFNPs) were synthesized by thermal plasma route for the first time. To check the efficiency of the developed MFNPs as magnetic hyperthermia agents, induction heating study was performed under an AC magnetic field (4 kA/m amplitude and 375 kHz frequency). The results demonstrated temperature increase to 50 degrees C within 2 s for bare MFNPs and 5 s for water dispersion of MFNPs. The specific absorption rate (SAR) of the MFNPs was found to be 403.78 Wg- 1 and 546.1 Wg- 1 using linear data fitting and Box-Lucas fitting methods respectively. These results were superior to those in the preceding reports using MFNPs as magnetic hyperthermia agents. Cytotoxicity assay on B16-F1 epithelial cells and A549 adenocarcinomic human alveolar basal epithelial cells proved high cell-viability of the synthesized MFNPs. Hence, our research demonstrated a thermal plasma-based synthesis of reproducible, and biocompatible MFNPs with superior performance which will improve accuracy and reduce side effects during targeted cancer treatment.

引用

页数：13

共 78 条

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