Advantages and challenges of polymer-lipid hybrid nanoparticles for the delivery of biotech drugs

被引：1
|
作者：
Ottonelli, Ilaria [1 ]
Baraldi, Cecilia [1 ]
Ruozi, Barbara [1 ]
Vandelli, Maria Angela [1 ]
Tosi, Giovanni [1 ]
Duskey, Jason T. [1 ]
机构：
[1] Univ Modena & Reggio Emilia, Dept Life Sci, NanotechLab, Via G Campi 103, I-41125 Modena, Italy
来源：
NANOMEDICINE | 2025年
关键词：
Polymer nanoparticles; nanoparticles; gene/drug delivery; targeting; vaccines;
D O I：
10.1080/17435889.2025.2457930
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
引用
收藏
页数：3
相关论文
共 50 条
  • [21] Dual redox/pH-responsive hybrid polymer-lipid composites: Synthesis, preparation, characterization and application in drug delivery with enhanced therapeutic efficacy
    Li, Juan
    Ma, Yuan Jun
    Wang, Yan
    Chen, Bo Zhi
    Guo, Xin Dong
    Zhang, Can Yang
    CHEMICAL ENGINEERING JOURNAL, 2018, 341 : 450 - 461
  • [22] A scalable and robust cationic lipid/polymer hybrid nanoparticle platform for mRNA delivery
    Meyer, Randall A.
    Hussmann, G. Patrick
    Peterson, Norman C.
    Santos, Jose Luis
    Tuesca, Anthony D.
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2022, 611
  • [23] Protein-Polymer Hybrid Nanoparticles for Drug Delivery
    Ge, Jun
    Neofytou, Evgenios
    Lei, Jiandu
    Beygui, Ramin E.
    Zare, Richard N.
    SMALL, 2012, 8 (23) : 3573 - 3578
  • [24] Doxorubicin and mitomycin C co-loaded polymer-lipid hybrid nanoparticles inhibit growth of sensitive and multidrug resistant human mammary tumor xenografts
    Prasad, Preethy
    Shuhendler, Adam
    Cai, Ping
    Rauth, Andrew M.
    Wu, Xiao Yu
    CANCER LETTERS, 2013, 334 (02) : 263 - 273
  • [25] Solid lipid nanoparticles and nanostructured lipid carriers as novel drug delivery systems: applications, advantages and disadvantages
    Ghasemiyeh, Parisa
    Mohammadi-Samani, Soliman
    RESEARCH IN PHARMACEUTICAL SCIENCES, 2018, 13 (04) : 288 - 303
  • [26] Development and optimization of methotrexate-loaded lipid-polymer hybrid nanoparticles for controlled drug delivery applications
    Tahir, Nayab
    Madni, Asadullah
    Balasubramanian, Vimalkumar
    Rehman, Mubashar
    Correia, Alexandra
    Kashif, Prince Muhammad
    Makila, Ermei
    Salonen, Jarno
    Santos, Helder A.
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2017, 533 (01) : 156 - 168
  • [27] DEVELOPMENT OF LIPID-POLYMER HYBRID NANOPARTICLES FOR TENDON REGENERATION
    Cerda, Sandra Lopez
    Fontana, Flavia
    Correia, Alexandra
    Wang, Shiqi
    Molinaro, Giuseppina
    Tello, Ruben Pareja
    Stoeckl, Johannes
    Celia, Christian
    Santos, Helder A.
    TISSUE ENGINEERING PART A, 2023, 29 (11-12) : 778 - 779
  • [28] Development of topical thymoquinone loaded polymer-lipid hybrid vesicular gel: in-vitro and ex-vivo evaluation
    Trivedi, Sagar
    Wadher, Kamlesh
    Umekar, Milind
    JOURNAL OF LIPOSOME RESEARCH, 2022, 32 (03) : 224 - 236
  • [29] Cationic lipid-polymer hybrid carrier for delivery of miRNA and peptides
    Salunkhe, Shubham A.
    Bajaj, Kiran
    Mittal, Anupama
    BIOMATERIALS ADVANCES, 2025, 173
  • [30] Influence of cationic lipid concentration on properties of lipid-polymer hybrid nanospheres for gene delivery
    Bose, Rajendran Jc
    Arai, Yoshie
    Ahn, Jong Chan
    Park, Hansoo
    Lee, Soo-Hong
    INTERNATIONAL JOURNAL OF NANOMEDICINE, 2015, 10 : 5367 - 5382
12345