Chinese expert consensus on diagnosis and treatment of radiation pneumonitis

被引:7
作者
Zhou, Caicun [1 ]
Yu, Jinming [2 ]
机构
[1] China Int Exchange & Promot Assoc Med & Hlth Care, Thorac Oncol Branch, Shanghai, Peoples R China
[2] Chinese Radiat Therapy Oncol Grp, Jinan, Shandong, Peoples R China
来源
PRECISION RADIATION ONCOLOGY | 2022年 / 6卷 / 03期
关键词
consensus; diagnosis; radiation pneumonitis; treatment; CELL LUNG-CANCER; RISK-FACTORS; CONCURRENT CHEMORADIOTHERAPY; POSTOPERATIVE RADIOTHERAPY; DOSE-ESCALATION; TOXICITY; THERAPY; AMIFOSTINE; NSCLC; METAANALYSIS;
D O I
10.1002/pro6.1169
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Radiotherapy is one of the main tumor treatment modalities that provides great survival benefits to patients with cancer. However, it is important to pay attention to the occurrence of adverse events after radiotherapy and take early measures. Radiation pneumonitis (RP) is a major adverse response in patients with cancer receiving thoracic radiotherapy, and it affects the quality of life and survival of patients. We analyzed the latest evidence on RP, and summarized research developments on the pathophysiological mechanism, risk factors, clinical manifestations, diagnosis and differential diagnosis, classification, treatment, and prognosis to form a consensus. With the development of comprehensive treatments, including immunotherapy, the diagnosis and identification of RP has become more complex, requiring multidisciplinary discussion and decision-making. In the future, it is critical to explore more effective treatments, various risk factors, and precautions for RP.
引用
收藏
页码:262 / 271
页数:10
相关论文
共 56 条
  • [1] Durvalumab after Chemoradiotherapy in Stage III Non-Small-Cell Lung Cancer
    Antonia, S. J.
    Villegas, A.
    Daniel, D.
    Vicente, D.
    Murakami, S.
    Hui, R.
    Yokoi, T.
    Chiappori, A.
    Lee, K. H.
    de Wit, M.
    Cho, B. C.
    Bourhaba, M.
    Quantin, X.
    Tokito, T.
    Mekhail, T.
    Planchard, D.
    Kim, Y. -C.
    Karapetis, C. S.
    Hiret, S.
    Ostoros, G.
    Kubota, K.
    Gray, J. E.
    Paz-Ares, L.
    de Castro Carpeno, J.
    Wadsworth, C.
    Melillo, G.
    Jiang, H.
    Huang, Y.
    Dennis, P. A.
    Ozguroglu, M.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2017, 377 (20) : 1919 - 1929
  • [2] Radiation-induced lung injury: current evidence
    Arroyo-Hernandez, Marisol
    Maldonado, Federico
    Lozano-Ruiz, Francisco
    Munoz-Montano, Wendy
    Nunez-Baez, Monica
    Arrieta, Oscar
    [J]. BMC PULMONARY MEDICINE, 2021, 21 (01)
  • [3] Clinical and Dosimetric Factors Predicting Grade ≥2 Radiation Pneumonitis After Postoperative Radiotherapy for Patients With Non-Small Cell Lung Carcinoma
    Boonyawan, Keeratikarn
    Gomez, Daniel R.
    Komaki, Ritsuko
    Xu, Yujin
    Nantavithya, Chonnipa
    Allen, Pamela K.
    Mohan, Radhe
    Liao, Zhongxing
    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2018, 101 (04): : 919 - 926
  • [4] Toxicity and outcome results of RTOG 9311: A phase I-II dose-escalation study using three-dimensional conformal radiotherapy in patients with inoperable non-small-cell lung carcinoma
    Bradley, J
    Graham, MV
    Winter, K
    Purdy, JA
    Komaki, R
    Roa, WH
    Ryu, JK
    Bosch, W
    Emami, B
    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2005, 61 (02): : 318 - 328
  • [5] A prospective study on radiation pneumonitis following conformal radiation therapy in non-small-cell lung cancer:: clinical and dosimetric factors analysis
    Claude, L
    Pérol, D
    Ginestet, C
    Falchero, L
    Arpin, D
    Vincent, M
    Martel, I
    Hominal, S
    Cordier, JF
    Carrie, C
    [J]. RADIOTHERAPY AND ONCOLOGY, 2004, 71 (02) : 175 - 181
  • [6] The CD73/Ado System-A New Player in RT Induced Adverse Late Effects
    de Leve, Simone
    Wirsdoerfer, Florian
    Jendrossek, Verena
    [J]. CANCERS, 2019, 11 (10)
  • [7] Analysis of Clinical and Dosimetric Factors Influencing Radiation-Induced Lung Injury in Patients with Lung Cancer
    Han, Shuiyun
    Gu, Feiying
    Lin, Gang
    Sun, Xiaojiang
    Wang, Yuezhen
    Wang, Zhun
    Lin, Qingren
    Weng, Denghu
    Xu, Yaping
    Mao, Weimin
    [J]. JOURNAL OF CANCER, 2015, 6 (11): : 1172 - 1178
  • [8] Pembrolizumab Plus Concurrent Chemoradiation Therapy in Patients With Unresectable, Locally Advanced, Stage III Non-Small Cell Lung Cancer The Phase 2 KEYNOTE-799 Nonrandomized Trial
    Jabbour, Salma K.
    Lee, Ki Hyeong
    Frost, Nikolaj
    Breder, Valeriy
    Kowalski, Dariusz M.
    Pollock, Theodore
    Levchenko, Evgeny
    Reguart, Noemi
    Martinez-Marti, Alex
    Houghton, Baerin
    Paoli, Jean-Baptiste
    Safina, Sufia
    Park, Keunchil
    Komiya, Takefumi
    Sanford, Amy
    Boolell, Vishal
    Liu, Hong
    Samkari, Ayman
    Keller, Steven M.
    Reck, Martin
    [J]. JAMA ONCOLOGY, 2021, 7 (09) : 1351 - 1359
  • [9] Radiation pneumonitis in patients with non-small-cell lung cancer receiving chemoradiotherapy and an immune checkpoint inhibitor: a retrospective study
    Jang, Jeong Yun
    Kim, Su Ssan
    Song, Si Yeol
    Kim, Yeon Joo
    Kim, Sung-woo
    Choi, Eun Kyung
    [J]. RADIATION ONCOLOGY, 2021, 16 (01)
  • [10] JENNINGS FL, 1962, ARCH PATHOL, V74, P351