Targeting undruggable protein KRAS for cancer therapy: novel opportunities and challenges

被引：0
|
作者：
Yang, Xin [1 ]
Li, Xiang [2 ]
Zhang, Yue-Lin [2 ]
Zhang, Sheng-Nan [1 ]
Zhang, Miao [1 ]
Sun, Chong [1 ]
Yang, Li [2 ]
Liu, Hong-Min [1 ,3 ,4 ]
Yuan, Shuo [1 ,3 ,4 ]
机构：
[1] Zhengzhou Univ, Henan Childrens Hosp, Zhengzhou Childrens Hosp, Childrens Hosp, 33 Longhu Outer Ring East Rd, Zhengzhou 450018, Peoples R China
[2] Zhengzhou Univ, Affiliated Hosp 3, Dept Obstet & Gynecol, Zhengzhou Key Lab Endometrial Dis Prevent & Treatm, Zhengzhou, Peoples R China
[3] Zhengzhou Univ, Sch Pharmaceut Sci, Zhengzhou, Peoples R China
[4] Zhengzhou Univ, Key Lab Adv Drug Preparat Technol, Zhengzhou, Peoples R China
来源：
FUTURE MEDICINAL CHEMISTRY | 2025年 / 17卷 / 02期
基金：
中国国家自然科学基金;
关键词：
KRAS inhibitor; anti-cancer; drug resistance; drug design; combination therapy; RAS; KRAS(G12D);
D O I：
10.1080/17568919.2024.2444865
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：143 / 147
页数：5
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