INVASIVE PNEUMOCOCCAL DISEASE IN PATIENTS FROMA PEDIATRIC HOSPITAL IN PERU, 2017-2020

被引：0

作者：

Marin-Portocarrero, Julio Guillermo ^{[1
,2
]}

Quispe-Sanchez, Alan ^{[1
]}

Charca-Rodriguez, Flor de Maria ^{[1
]}

Atamari-Anahui, Noe ^{[1
,3
]}

机构：

[1] Inst Nacl Salud Nino Brena, Lima, Peru

[2] Univ Nacl Federico Villarreal, Fac Human Med, Lima, Peru

[3] Univ San Ignacio Loyola, Res Unit Hlth Evidence Generat & Synth, Vicerrectorado Invest, Lima, Peru

来源：

REVISTA PERUANA DE MEDICINA EXPERIMENTAL Y SALUD PUBLICA | 2022年 / 39卷 / 04期

关键词：

Streptococcus pneumoniae; Pneumococcal Vaccines; Child; Peru (Source: MeSH NLM); STREPTOCOCCUS-PNEUMONIAE; CHILDREN;

D O I：

10.17844/rpmesp.2022.394.12054

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

This study aimed to describe the clinical characteristics, serotypes, and antibiotic susceptibility in patients with invasive pneumococcal disease (IPD). The medical records of patients with IPD who were hospitalized at the Instituto Nacional de Salud del Ni & ntilde;o-Bre & ntilde;a (Lima, Peru) were reviewed. We evaluated 29 patients. The median age was 1.9 years (interquartile range: 1 to 4 years). Of the sample, 51.7% were women and the most frequent clinical form of IPD was bacteremia in 18 (62.1%) patients; 65.5% had a complete vaccination schedule, according to the Peruvian Ministry of Health. Germ isolation was performed from blood samples in 82.8% of patients. Antibiotic resistance to erythromycin (55.2%) was the most frequent, followed by resistance to trimethoprim-sulfamethoxazole (48.3%) and penicillin (24.1%). The isolated serotypes were 6C, 19A, 23A and 24F. One patient died of meningitis. In conclusion, IPD was more frequent in children aged one to five years and the most frequent clinical form was bacteremia. Five serotypes reported in previous studies were found to be resistant to penicillin and erythromycin.

引用

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