Role of breast MRI BI-RADS descriptors in discrimination of non-mass enhancement lesion: A systematic review & meta-analysis

被引：0
作者：
Arian, Arvin [1 ]
Athar, Mohammad Mobin Teymouri [2 ]
Nouri, Shadi [3 ]
Ghorani, Hamed [4 ]
Khalaj, Fattaneh [4 ]
Hejazian, Seyyed Sina [5 ]
Shaghaghi, Shiva [6 ]
Beheshti, Rasa [7 ,8 ]
机构：
[1] Univ Tehran Med Sci, Imam Khomeini Hosp, Canc Res Inst, Adv Diagnost & Intervent Radiol ADIR, Tehran, Iran
[2] Shahid Beheshti Univ Med Sci, Sch Med, Tehran, Iran
[3] Arak Univ Med Sci, Radiol, Arak, Iran
[4] Univ Tehran Med Sci, Adv Diagnost & Intervent Radiol Res Ctr ADIR, Tehran, Iran
[5] Tabriz Univ Med Sci, Neurosci Res Ctr, Tabriz, Iran
[6] Univ Penn, Radiol Dept, Med Image Proc Grp MIPG, Philadelphia, PA USA
[7] Tabriz Univ Med Sci, Student Res Comm, Tabriz, Iran
[8] Tabriz Univ Med Sci, Iranian EBM Ctr, Res Ctr Evidence Based Med, Joanna Briggs Inst Ctr Excellence, Golgasht St, Tabriz, East Azerbaijan, Iran
来源：
EUROPEAN JOURNAL OF RADIOLOGY | 2025年 / 185卷
关键词：
Breast neoplasms; Magnetic resonance imaging; Non-mass enhancement; Systematic review; Meta-analysis; POSITIVE PREDICTIVE-VALUE; NONMASS ENHANCEMENT; DIAGNOSTIC PERFORMANCE; DIFFERENTIAL-DIAGNOSIS; INTERPRETATION MODEL; 5TH EDITION; FEATURES; WOMEN; MALIGNANCY; PATTERNS;
D O I：
10.1016/j.ejrad.2025.111996
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Objectives:: To evaluate the association of BI-RADS 5th edition distribution and type of enhancement descriptors with the malignancy of non-mass enhancement (NME) lesions. Methods:: Medline via PubMed, Scopus, Web of Science, ProQuest, and Embase databases were systematically searched from January 2013 to July 2022 for original studies, written in English, reporting the positive predictive value (PPV) of individual BI-RADS 5th edition descriptors (distribution and type of enhancement) of NME lesions. Risk of bias and quality of included studies were assessed by QUADAS 2 appraisal tool. Odds ratio (OR) of pathologically confirmed malignant results in each distribution and internal enhancement were pooled in a metaanalysis. Results:: Eight studies for a total of 1095 lesions were included. The pooled OR of malignancy for linear, focal, segmental, regional, multiple region, and diffuse distributions are 0.70 (95%CI: 0.44-1.14), 0.37 (95% CI: 0.26-0.54), 2.42 (95% CI: 1.62-3.62), 0.56 (95% CI: 0.11-2.79), 2.80 (95% CI: 0.96-8.21), and 3.35 (95% CI: 0.59-19.04), respectively. The pooled OR of malignancy for homogenous, heterogeneous, clustered ring enhancement, and clumped enhancement are 0.39 (95% CI: 0.23-0.67), 0.59 (95% CI: 0.40-0.85), 2.92 (95% CI: 1.86-4.57), and 1.49 (95% CI: 0.96-2.32), respectively. Conclusion:: Based on a meta-analysis of 8 studies and more than one thousand non-mass enhancing lesions, diffuse, multiple regions and clustered ring descriptors of enhancement have the highest pooled OR for malignancy.
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页数：13
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