New Insights on Hepatitis B Virus Viral Transcription in Single Hepatocytes

被引：0

作者：

Peng, Bo ^{[1
]}

Pan, Lixia ^{[1
]}

Li, Wenhui ^{[1
,2
]}

机构：

[1] Natl Inst Biol Sci, Beijing 102206, Peoples R China

[2] Tsinghua Univ, Tsinghua Inst Multidisciplinary Biomed Res, Beijing 100084, Peoples R China

来源：

VIRUSES-BASEL | 2024年 / 16卷 / 12期

关键词：

HBV; transcription; single cell; MULTI-OMICS DATA; X PROTEIN; ANALOG THERAPY; HUMAN LIVERS; IN-SITU; VIREMIA; SMC5/6;

D O I：

10.3390/v16121828

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The hepatitis B virus (HBV) infects approximately 290 million people globally, with chronic infection sustained by persistent viral gene expression. Recent single-cell analyses of HBV viral transcripts have uncovered novel features of HBV transcription and provided fresh insights into its regulation at the single-cell level. In this review, we summarize the latest advancements in understanding HBV viral transcription in individual hepatocytes and highlight emerging technologies that hold promise for future research.

引用

页数：8

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