Concomitant Interstitial Pneumonia and Disseminated BCG Infection after Intravesical BCG Therapy: A Case Report

被引：0

作者：

Mochizuki, Fumi ^{[1
]}

Hanazawa, Midori ^{[1
]}

Komine, Manabu ^{[2
]}

Sunabe, Hiroya ^{[1
]}

Koyanagi, Sayumi ^{[1
]}

Yamazaki, Yuki ^{[1
]}

Watanabe, Ayumi ^{[1
]}

Shimada, Takafumi ^{[1
]}

Obara, Kazuki ^{[1
]}

Iijima, Hiroaki ^{[1
]}

Kurishima, Koichi ^{[1
]}

Ishikawa, Hiroichi ^{[1
]}

机构：

[1] Tsukuba Med Ctr Hosp, Dept Resp Med, Tsukuba, Japan

[2] Tsukuba Med Ctr Hosp, Dept Urol, Tsukuba, Japan

来源：

INTERNAL MEDICINE | 2024年

关键词：

interstitial pneumonia; disseminated BCG infection; intravesical BCG; Mycobacterium bovis BCG; BACILLUS-CALMETTE-GUERIN; BLADDER; IMMUNOTHERAPY; COMPLICATIONS;

D O I：

10.2169/internalmedicine.4659-24

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

An 83-year-old man presented with persistent fever after intravesical BCG therapy for bladder cancer. Chest computed tomography (CT) and bronchoscopy revealed diffuse ground-glass opacities with multiple micronodules and lymphocyte-predominant bronchoalveolar lavage fluid with a high CD4/CD8 ratio, respectively. Therefore, corticotherapy for interstitial pneumonia was initiated. Anti-fast staining of the respiratory specimens was negative; however, anti-tuberculosis treatment was added based on CT findings suggesting disseminated BCG infection. Fifty days post-admission, Mycobacterium bovis BCG was identified in the initial sputum cultures. Concomitant interstitial pneumonia and BCG infection should be considered in patients with abnormal chest imaging following intravesical BCG therapy.

引用

页数：5

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