Case reports of Strongyloides stercoralis infection in three patients with haematological malignancies

被引：0

作者：

Samsudin, N. ^{[1
,2
]}

Noordin, R. ^{[4
,5
]}

Anuar, N. S. ^{[5
]}

Rahumatullah, A. ^{[5
]}

Abdullah, A. D. G. ^{[3
]}

Husin, A. ^{[3
]}

Mohamed, Z. ^{[1
]}

机构：

[1] Univ Sains Malaysia, Sch Med Sci, Dept Med Microbiol & Parasitol, Kubang Kerian 16150, Malaysia

[2] Univ Malaysia Sarawak, Dept Pathol, Fac Med & Hlth Sci, Kota Samarahan 94300, Sarawak, Malaysia

[3] Univ Sains Malaysia, Sch Med Sci, Dept Internal Med, Clin Hematol Unit, Kubang Kerian 16150, Malaysia

[4] Univ Kebangsaan Malaysia, Fac Med, Dept Parasitol & Med Entomol, Kuala Lumpur 56000, Malaysia

[5] Univ Sains Malaysia, Inst Res Mol Med, George Town 11800, Malaysia

来源：

TROPICAL BIOMEDICINE | 2024年 / 41卷 / 04期

关键词：

Strongyloides stercoralis; hematological malignancies; real-time PCR; ELISA; SsRapid (R); DIAGNOSIS;

D O I：

10.47665/tb.41.4.001

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Strongyloidiasis is a parasitic nematode infection mainly caused by Strongyloides stercoralis. Immunocompromised conditions, particularly cancer patients treated with chemotherapy and corticosteroids, have a significant risk of developing Strongyloides hyperinfection. The lack of a gold standard laboratory method to rule out this infection and the insensitivity of microscopic stool examination due to low and intermittent larvae output in stool contribute to the low detection rate of this infection. We present three cases of strongyloidiasis in adults with haematological malignancies and significant eosinophilia in the early course of their cancer. Two patients were diagnosed with a combination of serological and molecular tests, and one was diagnosed serologically. Ivermectin at 200 mcg/kg/day for two days was commenced for all patients; unfortunately, one patient succumbed.

引用

页码：422 / 426

页数：5

共 27 条

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