Concentrated autologous bone marrow injection in the surgical treatment of scaphoid non-union

被引:0
作者
Maincourt, Pierre [1 ,2 ]
Andro, Christophe [2 ]
Perchoc, Arnaud [2 ]
Daoulas, Thomas [3 ]
Hu, Weiguo [2 ]
Perruisseau-Carrier, Anne [4 ,5 ]
机构
[1] Cavale Blanche Hosp, Dept Plast Reconstruct & Aesthet Surg, Blvd Tanguy Prigent, F-29200 Brest, France
[2] Clermont Tonnerre Hosp, Dept Orthopaed & Traumatol Surg, F-29200 Brest, France
[3] Cavale Blanche Hosp, Dept Orthopaed & Traumatol Surg, Blvd Tanguy Prigent, F-29200 Brest, France
[4] Grenoble Alpes Univ Hosp, Dept Hand Surg, F-38000 Grenoble, France
[5] Grenoble Alpes Univ, TIMC Lab, F-38700 La Tronche, France
关键词
Scaphoid non-union; Stem cells; Regenerative medicine; Bone healing;
D O I
10.1016/j.hansur.2024.102069
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
New surgical techniques for the treatment of scaphoid non-union, developed in the last two decades, now enable a healing rate of 80-90%. However, no consensus exists for the surgical treatment of non-union. On the other hand, regenerative medicine techniques have enriched the therapeutic armamentarium for non-union, especially in the lower limbs, with the use of autologous concentrated bone marrow injection using autologous osteogenic precursors to create a favorable microenvironment for bone healing. This technique has the advantages of being inexpensive, easily accessible and applicable in scaphoid non-union as a biological adjuvant to surgery, to improve both healing times and rates. We report 6-month clinical results for the first patient receiving autologous concentrated bone marrow injection associated to scaphoid screw fixation in our center. (c) 2025 SFCM. Published by Elsevier Masson SAS. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
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页数:3
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