PERINATAL ACETAMINOPHEN TOXICITY IS MEDIATED BY CYTOCHROME P450 2E1 (CYP2E1) IN A TIME AND CELL TYPE SPECIFIC MANNER

被引：0
|
作者：
Golden, E. [1 ]
Zheng, L. [1 ]
Grayck, M. R. [1 ]
Li, Z. [2 ]
Talaba, N. [2 ]
McCulley, D. [2 ]
Wright, C. J. [1 ]
机构：
[1] Univ Colorado, Sch Med, Aurora, CO USA
[2] Univ Calif San Diego, San Diego, CA USA
来源：
JOURNAL OF INVESTIGATIVE MEDICINE | 2024年 / 72卷 / 01期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
63
引用
收藏
页码：72 / 73
页数：2
相关论文
共 50 条
  • [21] The effect of lycopene on the total cytochrome P450, CYP1A2 and CYP2E1
    Louisa, Melva
    Suyatna, Frans D.
    Setiawati, Arini
    Jusman, Sri W. A.
    MEDICAL JOURNAL OF INDONESIA, 2009, 18 (04) : 233 - 238
  • [22] Role of cytochrome P450 2E1 in protein nitration and ubiquitin-mediated degradation during acetaminophen toxicity
    Abdelmegeed, Mohamed A.
    Moon, Kwan-Hoon
    Chen, Chi
    Gonzalez, Frank J.
    Song, Byoung-Joon
    BIOCHEMICAL PHARMACOLOGY, 2010, 79 (01) : 57 - 66
  • [23] Cytochrome P450 2E1 (CYP2E1) is essential for acrylonitrile metabolism to cyanide: Comparative studies using CYP2E1-null and wild-type mice
    Wang, HB
    Chanas, B
    Ghanayem, BI
    DRUG METABOLISM AND DISPOSITION, 2002, 30 (08) : 911 - 917
  • [24] Serum Autoantibodies Against Cytochrome P450 2E1 (CYP2E1) Predict Severity of Necroinflammation of Recurrent Hepatitis C
    Rigamonti, C.
    Vidali, M.
    Donato, M. F.
    Sutti, S.
    Occhino, G.
    Ivaldi, A.
    Arosio, E.
    Agnelli, F.
    Rossi, G.
    Colombo, M.
    Albano, E.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2009, 9 (03) : 601 - 609
  • [25] Inactivation of cytochrome P450 2E1 by capsaicin
    Smeal, SJ
    Reilly, CA
    Yost, GS
    FASEB JOURNAL, 2002, 16 (05): : A940 - A941
  • [26] Human and minipig cytochrome P450 2E1
    Baranová, J
    Anzenbacherová, E
    Zuber, R
    Anzenbacher, P
    Soucek, P
    CYTOCHROMES P450, BIOCHEMISTRY, BIOPHYSICS AND DRUG METABOLISM, 2003, : 143 - 147
  • [27] Cytochrome P450 2E1 (CYP2E1) is the principal enzyme responsible for urethane metabolism: Comparative studies using CYP2E1-null and wild-type mice
    Hoffler, U
    El-Masri, HA
    Ghanayem, BI
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2003, 305 (02): : 557 - 564
  • [28] Acetone catabolism by cytochrome P450 2E1: Studies with CYP2E1-null mice
    Bondoc, FY
    Bao, ZP
    Hu, WY
    Gonzalez, FJ
    Wang, YY
    Yang, CS
    Hong, JY
    BIOCHEMICAL PHARMACOLOGY, 1999, 58 (03) : 461 - 463
  • [29] Increased Hepatic Cytochrome P450 2E1 (CYP2E1) Activity in Children with Biopsy-proven Nonalcoholic Steatohepatitis (NASH)
    Bozic, Molly A.
    Molleston, Jean P.
    Jones, David R.
    Saxena, Romil
    Klipsch, Ann
    Chalasani, Naga P.
    HEPATOLOGY, 2012, 56 : 733A - 733A
  • [30] Phyllanthus urinaria extract attenuates acetaminophen induced hepatotoxicity: Involvement of cytochrome P450 CYP2E1
    Hau, Desmond Kwok Po
    Gambari, Roberto
    Wong, Raymond Siu Ming
    Yuen, Chun Wah Marcus
    Cheng, Gregory Yin Ming
    Tong, Cindy Sze Wai
    Zhu, Guo Yuan
    Leung, Alexander Kai Man
    Lai, Paul Bo San
    Lau, Fung Yi
    Chan, Andrew Kit Wah
    Wong, Wai Yeung
    Kok, Stanton Hon Lung
    Cheng, Chor Hing
    Kan, Chi Wai
    Chan, Albert Sun Chi
    Chui, Chung Hin
    Tang, Johnny Cheuk On
    Fong, David Wang Fun
    PHYTOMEDICINE, 2009, 16 (08) : 751 - 760
12345